Discovery of 1,2-Naphthoquinone Derivatives as Potent p53-MDM2 Interaction Inhibitors

被引：0
|
作者：
Jung, Myoung Eun [1 ]
Go, Areum [1 ]
Yoo, Dabin [2 ]
Chae, Jong-Hak [1 ]
Jeon, Moon-Kook [1 ]
Lim, Byungho [1 ]
Choi, Gildon [1 ,2 ]
机构：
[1] Korea Res Inst Chem Technol, Therapeut & Biotechnol Div, Daejeon 34114, South Korea
[2] UST, Med Chem & Pharmacol Major, KRICT Sch, Daejeon 34113, South Korea
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2019年 / 40卷 / 12期
关键词：
p53; MDM2; Protein-protein interaction; PPI inhibitor; 1,2-naphthoquinone; P53; CANCER; DESIGN;
D O I：
10.1002/bkcs.11897
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Discovery of 1,2-naphthoquinone analogues as potent p53-MDM2 interaction inhibitors.
引用
收藏
页码：1236 / 1239
页数：4
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