An easy and efficient approach for the installation of alkoxycarbonyl protecting groups on carbohydrate hydroxyls

被引：30

作者：

Adinolfi, M ^{[1
]}

Barone, G ^{[1
]}

Guariniello, L ^{[1
]}

Iadonisi, A ^{[1
]}

机构：

[1] Univ Naples Federico II, Dipartimento Chim Organ & Biol, I-80134 Naples, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 48期

关键词：

alkoxycarbonyl group; N; '-tetramethylethylenediamine; carbohydrates; protecting groups;

D O I：

10.1016/S0040-4039(00)01673-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkoxycarbonyl groups can be readily installed on carbohydrates by reaction with the corresponding chloroformates in the presence of TMEDA at low temperature. The mild reaction conditions can be modulated to attain regioselective protections. (C) 2000 Elsevier Science Ltd. Ail rights reserved.

引用

页码：9305 / 9309

页数：5

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