A community-based study of human immunodeficiency virus type 2 provirus load in a rural village in West Africa

被引：60

作者：

Ariyoshi, K

Berry, N

Wilkins, A

Ricard, D

Aaby, P

Naucler, A

Ngom, PT

Jobe, O

Jaffar, S

Dias, F

Tedder, RS

Whittle, H

机构：

[1] UCL, SCH MED, DIV VIROL, LONDON W1N 8AA, ENGLAND

[2] STATE SERUM INST, DANISH EPIDEMIOL SCI CTR, COPENHAGEN, DENMARK

[3] NATL BACTERIOL LAB, S-10521 STOCKHOLM, SWEDEN

[4] LAB NACL SAUDE PUBL, BISSAU, GUINEA BISSAU

来源：

JOURNAL OF INFECTIOUS DISEASES | 1996年 / 173卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1093/infdis/173.1.245

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A community-based study of provirus load in human immunodeficiency virus (HIV) type 2-infected subjects was done in a rural village in Guinea-Bissau. HIV-2 provirus load varied considerably, with a geometric mean of 124.3 (95% confidence interval, 86.0-179.6) copies/10(5) CD4 cells, which is a level similar to that found in HIV-1 infection. Neither malaria parasitemia, active syphilis, or human T cell leukemia virus coinfection significantly influenced provirus load, nor did age, Eleven of 104 HIV-2-infected subjects had died after 3 years of follow-up; 9 of those who died had a high provirus load of greater than or equal to 100 copies/10(5) CD4 cells and a relatively low CD4 cell percentage of < 29%.

引用

收藏

页码：245 / 248

页数：4

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