Near infrared-fluorescent and magnetic resonance imaging molecular probe with high T1 relaxivity for in vivo multimodal imaging

被引：33
作者：
Guo, Kevin [1 ]
Berezin, Mikhail Y. [1 ]
Zheng, Jie [1 ]
Akers, Walter [1 ]
Lin, Franck [2 ]
Teng, Bao [3 ]
Vasalatiy, Olga [3 ]
Gandjbakhche, Amir [4 ]
Griffiths, Gary L. [3 ]
Achilefu, Samuel [1 ,2 ,5 ]
机构：
[1] Washington Univ, Dept Radiol, St Louis, MO 63110 USA
[2] Washington Univ, Dept Biomed Engn, St Louis, MO 63110 USA
[3] NHLBI, Imaging Probe Dev Ctr, NIH, Bethesda, MD 20892 USA
[4] Eunice Shriver NICHD, NIH, Bethesda, MD 20892 USA
[5] Washington Univ, Dept Biochem & Mol Biophys, St Louis, MO 63110 USA
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 21期
基金：
美国国家卫生研究院;
关键词：
MRI CONTRAST AGENTS; HUMAN SERUM-ALBUMIN; GD-DTPA; RELAXATION; NANOPARTICLE; LIFETIME; DESIGN; MS-325;
D O I：
10.1039/c000536c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new gadolinium chelating NIR fluorescent molecular probe increases T-1 relaxivity of water protons, facilitating combined optical and magnetic resonance imaging.
引用
收藏
页码：3705 / 3707
页数：3
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