Macular disease detection with a swept-source optical coherence tomography-based biometry device in patients scheduled for cataract surgery

PURPOSE: To assess the sensitivity and specificity for detecting macular disease with a new optical biometry device with swept-source optical coherence tomography (SS-OCT) used before cataract surgery. SETTING: Hanusch Hospital, Vienna, Austria. DESIGN: Consecutive case series. METHODS: This study included patients with or without macular disease. All patients were scanned using the new biometry device (IOLMaster 700), which allows a 1.0 mm central retinal scan using SS-OCT technology. Also, all eyes were assessed using a dedicated retinal OCT device (RTVue) on the same day. Two experienced examiners and 1 ophthalmology resident graded all scans individually. Sensitivity and specificity for detecting macular disease were assessed, as were the receiver operating characteristic curves. RESULTS: Of the 125 eyes included, 5 were excluded from the analysis, 65 had a macular disease, and 55 were healthy. The sensitivity of the biometry device was moderate (between 42% and 68%), and the specificity was high (89% to 98%). Intraobserver reproducibility for assessing the biometry device was 88.3%. CONCLUSIONS: The biometry device with SS-OCT provided useful information concerning the macula, especially for intraretinal fluid and macular holes. However, it cannot replace a macular OCT device. (C) 2016 The Authors. Published by Elsevier Inc. on behalf of ASCRS and ESCRS.