Usefulness of hyperglycemia in predicting renal and myocardial injury in patients with diabetes mellitus undergoing percutaneous coronary intervention

被引:9
作者
Robertson, BJ
Gascho, JA
Gabbay, RA
McNulty, PH
机构
[1] Penn State Univ, Coll Med, Div Cardiol, Hershey, PA 17033 USA
[2] Penn State Univ, Coll Med, Div Endocrinol & Metab, Hershey, PA 17033 USA
关键词
D O I
10.1016/j.amjcard.2004.06.059
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A retrospective analysis of 165 patients who had diabetes mellitus and underwent percutaneous coronary intervention (PCI) between 1998 and 2003 demonstrated that those whose plasma glucose levels were greater than or equal to 200 mg/dl before PCI exhibited greater creatine phosphokinase release and serum creatinine increases after PCI. These observations identified hyperglycemia as a potentially modifiable mediator of myocardial and renal injuries in patients who have diabetes and have undergone PCI. (C) 2004 by Excerpta Medica, Inc.
引用
收藏
页码:1027 / 1029
页数:3
相关论文
共 18 条
[1]   Significance of mild transient release of creatine kinase-MB fraction after percutaneous coronary interventions [J].
Abdelmeguid, AE ;
Topol, EJ ;
Whitlow, PL ;
Sapp, SK ;
Ellis, SG .
CIRCULATION, 1996, 94 (07) :1528-1536
[2]   Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multivessel disease - The bypass angioplasty revascularization investigation (BARI) [J].
Alderman, E ;
Bourassa, M ;
Brooks, MM ;
Califf, R ;
Chaitman, B ;
Detre, K ;
Faxon, DP ;
Feit, F ;
Frye, RL ;
Hardison, RM ;
Holmes, D ;
Holubkov, R ;
Kouchoukos, N ;
Krone, R ;
Rogers, W ;
Rosen, AD ;
Schaff, H ;
Schwartz, L ;
Siewers, AS ;
Sopko, G ;
SuttonTyrrell, K ;
Whitlow, P .
CIRCULATION, 1997, 96 (06) :1761-1769
[3]  
*AM HEART ASS, 1999, 2000 HEART STROK STA
[4]   Relationship between diabetes mellitus and long-term survival after coronary bypass and angioplasty [J].
Barsness, GW ;
Peterson, ED ;
Ohman, EM ;
Nelson, CL ;
DeLong, ER ;
Reves, JG ;
Smith, PK ;
Anderson, RD ;
Jones, RH ;
Mark, DB ;
Califf, RM .
CIRCULATION, 1997, 96 (08) :2551-2556
[5]   Induction of hyperinsulinemia combined with hyperglycemia and hypertriglyceridemia increases plasminogen activator inhibitor 1 in blood in normal human subjects [J].
Calles-Escandon, J ;
Mirza, SA ;
Sobel, BE ;
Schneider, DJ .
DIABETES, 1998, 47 (02) :290-293
[6]   Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat [J].
Ceriello, A ;
Quagliaro, L ;
D'Amico, M ;
Di Filippo, C ;
Marfella, R ;
Nappo, F ;
Berrino, L ;
Rossi, F ;
Giugliano, D .
DIABETES, 2002, 51 (04) :1076-1082
[7]   Postprocedure creatine kinase-MB elevation and baseline left ventricular dysfunction predict one-year mortality after percutaneous coronary intervention [J].
Dangas, G ;
Mehran, R ;
Feldman, D ;
Stoyioglou, A ;
Pichard, AD ;
Kent, KM ;
Satler, LF ;
Fahy, M ;
Lansky, AJ ;
Stone, GW ;
Leon, MB .
AMERICAN JOURNAL OF CARDIOLOGY, 2002, 89 (05) :586-+
[8]   Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with Type II diabetes mellitus [J].
Gresele, P ;
Guglielmini, G ;
De Angelis, M ;
Ciferri, S ;
Ciofetta, M ;
Falcinelli, E ;
Lalli, C ;
Ciabattoni, G ;
Davì, G ;
Bolli, GB .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (06) :1013-1020
[9]   The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency [J].
Gruberg, L ;
Mintz, GS ;
Mehran, R ;
Dangas, G ;
Lansky, AJ ;
Kent, KM ;
Pichard, AD ;
Satler, LF ;
Leon, MB .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (05) :1542-1548
[10]   Creatine kinase-MB enzyme elevation following successful saphenous vein graft intervention is associated with late mortality [J].
Hong, MK ;
Mehran, R ;
Dangas, G ;
Mintz, GS ;
Lansky, AJ ;
Pichard, AD ;
Kent, KM ;
Satler, LF ;
Stone, GW ;
Leon, MB .
CIRCULATION, 1999, 100 (24) :2400-2405