A common ground for pain and depression

被引:42
作者
Tappe-Theodor, Anke [1 ]
Kuner, Rohini [1 ]
机构
[1] Heidelberg Univ, Pharmacol Inst, Heidelberg, Germany
关键词
ANTIDEPRESSANTS;
D O I
10.1038/s41593-019-0499-8
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive symptoms in chronic pain.
引用
收藏
页码:1612 / 1614
页数:4
相关论文
共 12 条
[11]   Emotional consequences of neuropathic pain: Insight from preclinical studies [J].
Yalcin, Ipek ;
Barthas, Florent ;
Barrot, Michel .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2014, 47 :154-164
[12]   Mitochondrial CHCHD2 and CHCHD10: Roles in Neurological Diseases and Therapeutic Implications [J].
Zhou, Wei ;
Ma, Dongrui ;
Tan, Eng-King .
NEUROSCIENTIST, 2020, 26 (02) :170-184