Cancer Sequencing Gets a Little More Personal

被引:2
作者
Prokunina-Olsson, Ludmila [1 ]
Chanock, Stephen J. [1 ]
机构
[1] NCI, Lab Translat Genom, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
关键词
GENOME-WIDE ASSOCIATION; RECURRENT GENE FUSIONS; REARRANGEMENT; CHROMOSOME; INSIGHTS;
D O I
10.1126/scitranslmed.3000929
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In this Perspective, we discuss a paper in this issue of Science Translational Medicine, in which Leary and colleagues present a new method based on massive, parallel, and near complete sequencing of individual tumor genomes. Their findings support the notion that cancer genomes house a spectrum of genetic alterations, many of which are unique to the individual tumor. More validation and a reduction in cost are required for this approach to become common in clinics.
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页数:3
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