Postpartum Depression: Current Status and Possible Identification Using Biomarkers

被引:45
作者
Yu, Yi [1 ,2 ]
Liang, Hong-Feng [1 ]
Chen, Jing [1 ,3 ]
Li, Zhi-Bin [1 ,3 ]
Han, Yu-Shuai [1 ,3 ]
Chen, Jia-Xi [1 ,3 ]
Li, Ji-Cheng [1 ,3 ]
机构
[1] Yangjiang Peoples Hosp, Cent Lab, Yangjiang, Peoples R China
[2] Zhejiang Univ Technol, Coll Chem Engn, Ctr Anal & Measurements, Hangzhou, Peoples R China
[3] Zhejiang Univ, Inst Cell Biol, Hangzhou, Peoples R China
来源
FRONTIERS IN PSYCHIATRY | 2021年 / 12卷
基金
中国国家自然科学基金;
关键词
postpartum depression; postnatal depression; biological markers; biomarkers; multi-omics; CORTICOTROPIN-RELEASING HORMONE; NEUROTROPHIC FACTOR BDNF; THYROID PEROXIDASE ANTIBODIES; GENE-ENVIRONMENT INTERACTION; RECEPTOR DNA METHYLATION; LOW-BIRTH-WEIGHT; VITAMIN-D STATUS; PERINATAL DEPRESSION; LATE PREGNANCY; SERUM ALLOPREGNANOLONE;
D O I
10.3389/fpsyt.2021.620371
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Postpartum depression (PPD) is a serious health issue that can affect about 15% of the female population within after giving birth. It often conveys significant negative consequences to the offsprings. The symptoms and risk factors are somewhat similar to those found in non-postpartum depression. The main difference resides in the fact that PPD is triggered by postpartum specific factors, including especially biological changes in the hormone levels. Patients are usually diagnosed using a questionnaire onsite or in a clinic. Treatment of PPD often involves psychotherapy and antidepressant medications. In recent years, there have been more researches on the identification of biological markers for PPD. In this review, we will focus on the current research status of PPD, with an emphasis on the recent progress made on the identification of PPD biomarkers.
引用
收藏
页数:16
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