Is sebocyte-derived leptin the missing link between hyperseborrhea, ductal hypoxia, inflammation and comedogenesis in acne vulgaris?

被引：13
作者：
Melnik, Bodo C. [1 ]
机构：
[1] Univ Osnabruck, Dept Dermatol Environm Med & Hlth Theory, Sedanstr 115, D-49090 Osnabruck, Germany
来源：
EXPERIMENTAL DERMATOLOGY | 2016年 / 25卷 / 03期
关键词：
acne; inflammasome; leptin; mTORC1; western diet; HOST-DEFENSE PEPTIDES; HUMAN BETA-DEFENSINS; HEALING-PROMOTING PEPTIDE; SOFT-TISSUE INFECTIONS; ANTIMICROBIAL PEPTIDES; HUMAN SKIN; IN-VITRO; PSEUDOMONAS-AERUGINOSA; STAPHYLOCOCCUS-AUREUS; INNATE DEFENSE;
D O I：
10.1111/exd.12917
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
[No abstract available]
引用
收藏
页码：181 / 182
页数：2
相关论文
共 169 条
[31]   The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds [J].
Duplantier, Allen J. ;
van Hoek, Monique L. .
FRONTIERS IN IMMUNOLOGY, 2013, 4
[32]   Mammalian Antimicrobial Peptides: Promising Therapeutic Targets Against Infection and Chronic Inflammation [J].
Dutta, Pujarini ;
Das, Santasabuj .
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 16 (01) :99-129
[33]   S100 proteins in the epidermis [J].
Eckert, RL ;
Broome, AM ;
Ruse, M ;
Robinson, N ;
Ryan, D ;
Lee, K .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 123 (01) :23-33
[34]   Granulysin expression increases with increasing clinical severity of psoriasis [J].
Elgarhy, L. H. ;
Shareef, M. M. ;
Moustafa, S. M. .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2015, 40 (04) :361-366
[35]   Targeting the Th17 pathway in psoriasis [J].
Elloso, M. Merle ;
Gomez-Angelats, Mireia ;
Fourie, Anne M. .
JOURNAL OF LEUKOCYTE BIOLOGY, 2012, 92 (06) :1187-1197
[36]   Esculentin 1-21: a linear antimicrobial peptide from frog skin with inhibitory effect on bovine mastitis-causing bacteria [J].
Enrique Islas-Rodriguez, Alfonso ;
Marcellini, Ludovica ;
Orioni, Barbara ;
Barra, Donatella ;
Stella, Lorenzo ;
Mangoni, Maria Luisa .
JOURNAL OF PEPTIDE SCIENCE, 2009, 15 (09) :607-614
[37]   Mechanisms of epithelial wound detection [J].
Enyedi, Balazs ;
Niethammer, Philipp .
TRENDS IN CELL BIOLOGY, 2015, 25 (07) :398-407
[38]   Lipid domains in bacterial membranes and the action of antimicrobial agents [J].
Epand, Richard M. ;
Epand, Raquel F. .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2009, 1788 (01) :289-294
[39]   Designing antimicrobial peptides: form follows function [J].
Fjell, Christopher D. ;
Hiss, Jan A. ;
Hancock, Robert E. W. ;
Schneider, Gisbert .
NATURE REVIEWS DRUG DISCOVERY, 2012, 11 (01) :37-51
[40]  
Foster D, 2014, OSTOMY WOUND MANAG, V60, P16
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