Is sebocyte-derived leptin the missing link between hyperseborrhea, ductal hypoxia, inflammation and comedogenesis in acne vulgaris?

被引:13
作者
Melnik, Bodo C. [1 ]
机构
[1] Univ Osnabruck, Dept Dermatol Environm Med & Hlth Theory, Sedanstr 115, D-49090 Osnabruck, Germany
关键词
acne; inflammasome; leptin; mTORC1; western diet; HOST-DEFENSE PEPTIDES; HUMAN BETA-DEFENSINS; HEALING-PROMOTING PEPTIDE; SOFT-TISSUE INFECTIONS; ANTIMICROBIAL PEPTIDES; HUMAN SKIN; IN-VITRO; PSEUDOMONAS-AERUGINOSA; STAPHYLOCOCCUS-AUREUS; INNATE DEFENSE;
D O I
10.1111/exd.12917
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
[No abstract available]
引用
收藏
页码:181 / 182
页数:2
相关论文
共 169 条
[1]   The Antimicrobial Heterodimer S100A8/S100A9 (Calprotectin) Is Upregulated by Bacterial Flagellin in Human Epidermal Keratinocytes [J].
Abtin, Arby ;
Eckhart, Leopold ;
Glaeser, Regine ;
Gmeiner, Ramona ;
Mildner, Michael ;
Tschachler, Erwin .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2010, 130 (10) :2423-2430
[2]   The human antimicrobial and chemotactic peptides LL-37 and α-defensins are expressed by specific lymphocyte and monocyte populations [J].
Agerberth, B ;
Charo, J ;
Werr, J ;
Olsson, B ;
Idali, F ;
Lindbom, L ;
Kiessling, R ;
Jörnvall, H ;
Wigzell, H ;
Gudmundsson, GH .
BLOOD, 2000, 96 (09) :3086-3093
[3]  
Ali RS, 2001, J INVEST DERMATOL, V117, P106
[4]  
Alibardi Lorenzo, 2010, Advances in Anatomy Embryology and Cell Biology, V207, P1
[5]   Will the wound-healing field earn its wings? [J].
Anderson, Aimee E. ;
Galko, Michael J. .
EXPERIMENTAL DERMATOLOGY, 2014, 23 (11) :809-810
[6]   Innate immunity in the lung: how epithelial cells fight against respiratory pathogens [J].
Bals, R ;
Hiemstra, PS .
EUROPEAN RESPIRATORY JOURNAL, 2004, 23 (02) :327-333
[7]   The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface [J].
Bals, R ;
Wang, XR ;
Zasloff, M ;
Wilson, JM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (16) :9541-9546
[8]   Pharmaceutical application of frog skin on full-thickness skin wound healing in mice [J].
Bazaz, Mahere Rezazade ;
Mashreghi, Mohammad ;
Shahri, Nasser Mahdavi ;
Mashreghi, Mansour ;
Asoodeh, Ahmad ;
Rassouli, Morteza Behnam ;
Golmohammadzadeh, Shiva .
PHARMACEUTICAL BIOLOGY, 2013, 51 (12) :1600-1606
[9]   Innate Immune Functions of α-Defensins in the Small Intestine [J].
Bevins, Charles L. .
DIGESTIVE DISEASES, 2013, 31 (3-4) :299-304
[10]   NMR Structures and Interactions of Antimicrobial Peptides with Lipopolysaccharide: Connecting Structures to Functions [J].
Bhattacharjya, Surajit .
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 16 (01) :4-15