Neurodegeneration in Huntington's disease involves loss of cystathionine γ-lyase

被引:39
作者
Paul, Bindu D. [1 ]
Snyder, Solomon H. [1 ,2 ,3 ]
机构
[1] Johns Hopkins Univ, Sch Med, Solomon H Snyder Dept Neurosci, Baltimore, MD 21218 USA
[2] Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD 21205 USA
[3] Johns Hopkins Univ, Sch Med, Dept Pharmacol & Mol Sci, Baltimore, MD 21205 USA
关键词
corpus striatum; cystathionine; -lyase; cysteine; hydrogen sulfide; Rhes; specificity protein-1 (SP1); CO; carbon monoxide; HD; Huntington's disease; Keap1; Kelch-like ECH-associated protein 1; NO; nitric oxide; Nrf2; nuclear factor erythroid 2-related factor 2; TAF4; TBP associated factor 4; TBP; TATA box binding protein; CYSTAMINE; MODEL;
D O I
10.4161/15384101.2014.950538
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:2491 / 2493
页数:3
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