Bis(indoline-2,3-diones):Versatile precursors for novel bis(2′,6′-dimethyl-2-oxo-1′H-spiro[indoline-3,4′-pyridine]-3′,5′-dicarbonitrile) derivatives

被引：19

作者：

Abdelmoniem, Amr M. ^{[1
]}

Elwahy, Ahmed H. M. ^{[1
]}

Abdelhamid, Ismail A. ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

ARKIVOC | 2016年

关键词：

Bis(indoline-2,3-diones); bis(spirooxindole); 1,4-dihydropyridine-3,5-dicarbonitrile; alkylation; condensation; SUBSTITUTED MACROCYCLIC LIGANDS; AZAENAMINES; CATALYST;

D O I：

10.3998/ark.5550190.0017.324

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 3-aminocrotononitrile with a series of bis(indoline-2,3-diones) afforded the corresponding bis(2',6'-dimethyl-2-oxo-1'H-spiro[indoline-3,4'-pyridine]-3', 5'-dicarbonitrile) derivatives in good to excellent yields.

引用

收藏

页码：304 / 312

页数：9

相关论文

共 33 条

[21] Construction of spiro[pyrrolidine-3,3′-oxindoles] -: Recent applications to the synthesis of oxindole alkaloids [J].

Marti, C ;

Carreira, EM .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2003, 2003 (12) :2209-2219

[22] Synthesis of Novel Benzo-substituted Macrocyclic Ligands Containing Thienothiophene Subunits [J].

Mekky, Ahmed E. M. ;

Elwahy, Ahmed H. M. .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 :E34-E41

[23] Synthesis, cytotoxicity, QSAR, and intercalation study of new diindenopyridine derivatives [J].

Miri, R ;

Javidnia, K ;

Hemmateenejad, B ;

Azarpira, A ;

Amirghofran, Z .

BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (10) :2529-2536

[24] Microwave-Assisted Catalyst Free Three Component Synthesis of Mono and Bis Spiro Pyrazolopyridines in Solvent Free Reaction [J].

Nikpassand, Mohammad ;

Fekri, Leila Zare ;

Jamshidi, Neda .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2015, 52 (05) :1580-1583

[25] Oxindole alkaloids. A novel non-biomimetic entry to (-)-horsfiline [J].

Palmisano, G ;

Annunziata, R ;

Papeo, G ;

Sisti, M .

TETRAHEDRON-ASYMMETRY, 1996, 7 (01) :1-4

[26]

Reddy CS, 2010, ACTA CHIM SLOV, V57, P726

[27]

Sayed O.M., 2015, J HETEROCYCL CHEM

[28] 3,4-Dimethyl-2,5-functionalized thieno[2,3-b]thiophenes: versatile precursors for novel bis-thiazoles [J].

Sayed, Osama M. ;

Mekky, Ahmed E. M. ;

Farag, Ahmad M. ;

Elwahy, Ahmad H. M. .

JOURNAL OF SULFUR CHEMISTRY, 2015, 36 (02) :124-134

[29] Synthesis of Oxazolo-, Thiazolo-, Pyrazolo-, and Imidazo-Fused Heterocycles by Multi-Component Reactions (Part 2) [J].

Shaaban, Mohamed R. ;

Elwahy, Ahmed H. M. .

CURRENT ORGANIC SYNTHESIS, 2014, 11 (04) :471-525

[30] β-Cyclodextrin as a supramolecular catalyst for the synthesis of dihydropyrano[2,3-c]pyrazole and spiro[indoline-3,4′-pyrano [2,3-c]pyrazole] in aqueous medium [J].

Tayade, Yogesh A. ;

Padvi, Swapnil A. ;

Wagh, Yogesh B. ;

Dalai, Dipak S. .

TETRAHEDRON LETTERS, 2015, 56 (19) :2441-2447

← 1 2 3 4 →