Primary Central Nervous System Lymphoma

被引：20

作者：

Sinicrope, Kaylyn ^{[1
]}

Batchelor, Tracy ^{[1
,2
,3
]}

机构：

[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, 55 Fruit St, Boston, MA 02114 USA

[2] Harvard Med Sch, Massachusetts Gen Hosp, Radiat Oncol, 55 Fruit St, Boston, MA 02114 USA

[3] Harvard Med Sch, Massachusetts Gen Hosp, Div Hematol & Oncol, 55 Fruit St, Boston, MA 02114 USA

来源：

NEUROLOGIC CLINICS | 2018年 / 36卷 / 03期

关键词：

Primary central nervous system lymphoma; Brain; Non-Hodgkin's lymphoma; Methotraxate; PRIMARY CNS LYMPHOMA; HIGH-DOSE METHOTREXATE; STEM-CELL TRANSPLANTATION; WHOLE-BRAIN RADIOTHERAPY; NON-HODGKINS-LYMPHOMA; MULTICENTER PHASE-II; INTERNATIONAL EXTRANODAL LYMPHOMA; RECURRENT PRIMARY CNS; LONG-TERM SURVIVAL; DEFERRED RADIOTHERAPY;

D O I：

10.1016/j.ncl.2018.04.008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Primary central nervous system lymphoma (PCNSL) is an aggressive form of non-Hodgkin lymphoma restricted to the central nervous system. Stereotactic biopsy is the gold standard for diagnosis of PCNSL. Extent of disease evaluation for patients with newly diagnosed PCNSL includes brain imaging, eye examination, cerebrospinal fluid assessment, body imaging, and bone marrow biopsy. Methotrexate-based chemotherapy is the standard induction for patients with PCNSL. Optimal consolidation therapy for PCNSL has not been defined, with several options feasible, including chemotherapy, high-dose chemotherapy, and autologous stem cell transplantation or whole-brain radiation therapy. Optimal treatment for relapsed and refractory PCNSL has not been defined.

引用

页码：517 / +

页数：17

共 88 条

[1] Primary central nervous system lymphoma: The Memorial Sloan-Kettering Cancer Center prognostic model [J].

Abrey, Lauren E. ;

Ben-Porat, Leah ;

Panageas, Katherine S. ;

Yahalom, Joachim ;

Berkey, Brian ;

Curran, Walter ;

Schultz, Christopher ;

Leibel, Steven ;

Nelson, Diana ;

Mehta, Minesh ;

DeAngelis, Lisa M. .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (36) :5711-5715

[2] Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma [J].

Abrey, LE ;

Batchelor, TT ;

Ferreri, AJM ;

Gospodarowicz, M ;

Pulczynski, EJ ;

Zucca, E ;

Smith, JR ;

Korfel, A ;

Soussain, C ;

DeAngelis, LM ;

Neuwelt, EA ;

O'Neill, BP ;

Thiel, E ;

Shenkier, T ;

Graus, F ;

van den Bent, M ;

Seymour, JF ;

Poortmans, P ;

Armitage, JO ;

Cavalli, F .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (22) :5034-5043

[3] Long-term survival in primary CNS lymphoma [J].

Abrey, LE ;

DeAngelis, LM ;

Yahalom, J .

JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (03) :859-863

[4] Upfront thiotepa, busulfan, cyclophosphamide, and autologous stem cell transplantation for primary CNS lymphoma: a single centre experience [J].

Alimohamed, Nimira ;

Daly, Andrew ;

Owen, Carolyn ;

Duggan, Peter ;

Stewart, Douglas A. .

LEUKEMIA & LYMPHOMA, 2012, 53 (05) :862-867

[5] Late cognitive and radiographic changes related to radiotherapy - Initial prospective findings [J].

Armstrong, CL ;

Hunter, JV ;

Ledakis, GE ;

Cohen, B ;

Tallent, EM ;

Goldstein, BH ;

Tochner, Z ;

Lustig, R ;

Judy, KD ;

Pruitt, A ;

Mollman, JE ;

Stanczak, EM ;

Jo, MY ;

Than, TL ;

Phillips, P .

NEUROLOGY, 2002, 59 (01) :40-48

[6] Primary intracerebral malignant lymphoma: report of 248 cases [J].

Bataille, B ;

Delwail, V ;

Menet, E ;

Vandermarcq, P ;

Ingrand, P ;

Wager, M ;

Guy, G ;

Lapierre, F .

JOURNAL OF NEUROSURGERY, 2000, 92 (02) :261-266

[7] Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: A report of NABTT 96-07 [J].

Batchelor, T ;

Carson, K ;

O'Neill, A ;

Grossman, SA ;

Alavi, J ;

New, P ;

Hochberg, F ;

Priet, R .

JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (06) :1044-1049

[8] RITUXIMAB MONOTHERAPY FOR PATIENTS WITH RECURRENT PRIMARY CNS LYMPHOMA [J].

Batchelor, T. T. ;

Grossman, S. A. ;

Mikkelsen, T. ;

Ye, X. ;

Desideri, S. ;

Lesser, G. J. .

NEUROLOGY, 2011, 76 (10) :929-930

[9] Surgical removal of primary central nervous system lymphomas (PCNSL) presenting as space occupying lesions: a series of 33 cases [J].

Bellinzona, M ;

Roser, F ;

Ostertag, H ;

Gaab, RM ;

Saini, M .

EJSO, 2005, 31 (01) :100-105

[10] Primary non-Hodgkin's lymphoma of the CNS treated with CHOD/BVAM or BVAM chemotherapy before radiotherapy: Long-term survival and prognostic factors [J].

Bessell, EM ;

Graus, F ;

Lopez-Guillermo, A ;

Lewis, SA ;

Villa, S ;

Verger, E ;

Petit, J .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2004, 59 (02) :501-508

← 1 2 3 4 5 6 7 8 9 →