Cell polarity oscillations in mitotic epithelia

被引:4
作者
Doerr, Sophia [1 ,2 ]
Ragkousi, Katerina [1 ,2 ]
机构
[1] Amherst Coll, Dept Biol, Amherst, MA 01002 USA
[2] Amherst Coll, Program Biochem & Biophys, Amherst, MA 01002 USA
关键词
SPINDLE ORIENTATION; PAR PROTEINS; DIVISION; JUNCTIONS; ORGANIZATION; LGL; MORPHOGENESIS; ARCHITECTURE; EFFICIENT; RIGIDITY;
D O I
10.1016/j.gde.2019.07.007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Epithelial organization and function depend on coordinated cell polarity. In developing tissues, proliferative epithelia maintain whole tissue polarity as individual cells undergo symmetric divisions. However, recent work has shown that cells in diverse epithelia remodel their polarity in a cell cycle-dependent manner. Here, we discuss the different mechanisms that drive mitotic polarity oscillations and their implications for tissue morphogenesis.
引用
收藏
页码:47 / 53
页数:7
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