What have we really learned from 'LIBERATE' trial?

被引:0
作者
Dimitrakakis, Constantine [1 ,2 ]
Tsigginou, Alexandra [1 ]
Keramopoulos, Dimitris [1 ]
Antsaklis, Aris [1 ]
机构
[1] Univ Athens, Sch Med, Dept Ob Gyn 1, Athens 11528, Greece
[2] NICHD, NIH, Bethesda, MD USA
关键词
Breast cancer; Tibolone; Recurrence; LIBERATE trial; Menopausal symptoms; BREAST-CANCER; POSTMENOPAUSAL WOMEN; VASOMOTOR SYMPTOMS; DOUBLE-BLIND; TIBOLONE; RECURRENCE; SURVIVAL; THERAPY;
D O I
10.1016/j.maturitas.2010.02.012
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
LIBERATE trial reports that Tibolone use increases the risk of recurrence in breast cancer patients with vasomotor symptoms. However, there are some uncertainties and weak points in the study. Emerged questions are if interpretation of the results could be extrapolated to all breast cancer patients or there are specific subgroups that could use Tibolone without increasing relapse rate. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:99 / 100
页数:2
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