2-Chloroquinoline-3-carbaldehydes: synthesis and reactions (2012-2017)

被引:11
作者
Massoud, Mohammed A. M. [1 ]
Bayoumi, Waleed A. [1 ,2 ]
Farahat, Abdelbasset A. [1 ]
El-Sayed, Magda A. [1 ,3 ]
Mansour, Basem [2 ]
机构
[1] Mansoura Univ, Dept Organ Pharmaceut Chem, Fac Pharm, Mansoura 35516, Egypt
[2] Delta Univ Sci & Technol, Fac Pharm, Dept Pharmaceut Chem, Gamasa, Egypt
[3] Horus Univ, Dept Pharmaceut Chem, Fac Pharm, New Damietta, Egypt
关键词
Aldehydes; aromatic nucleophilic substitution; 2-chloroquinoline-3-carbaldehydes; cyclization; quinolines; Vilsmeier-Haack reaction; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; FUNCTIONALIZED CHROMENES; MULTICOMPONENT REACTIONS; FUSED HETEROCYCLES; QUINOLINE; DERIVATIVES; INHIBITORS; ISOCYANIDE;
D O I
10.24820/ark.5550190.p010.399
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This review discuss in details the synthesis and reactions of 2-chloroquinoline-3-carbaldehydes during years of 2012-2017. The reactions are subdivided into groups, according to type of reaction, including reactions of both chloro and/or aldehyde substituents. Most applied reactions have been successfully utilized for synthesis of different biologically and pharmacologically active derivatives.
引用
收藏
页码:244 / 287
页数:44
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