Synthesis of a new tricyclic 3-(tetrazol-5-yl)pyridine system from 2-(azidomethyl)nicotinonitriles

被引：9

作者：

Bliznets, IV

Shorshnev, SV

Aleksandrov, GG

Stepanov, AE

Lukyanov, SM

机构：

[1] ChemBridge Corp, Moscow 119435, Russia

[2] MV Lomonosov Moscow State Acad Fine Chem Technol, Moscow 119435, Russia

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 49期

关键词：

side chain oxidation; methyl group functionalization; intramolecular cycloaddition; cyano group; azidomethyl group; fused tetrazole; nicotinonitriles;

D O I：

10.1016/j.tetlet.2004.10.016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Methyl-3-cyanopyridines were converted into the corresponding 2-azidomethyl derivatives, which then underwent an intramolecular cycloaddition reaction. A novel heterocyclic system containing a 3-(tetrazol-5-yl)pyridine unit was obtained in this way. (C) 2004 Elsevier Ltd. All rights reserved.

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收藏

页码：9127 / 9130

页数：4

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