Clozapine-induced agranulocytosis: a case report - Immunopathophysiological considerations

被引：3
|
作者：
van de Loosdrecht, AA
Faber, HJ
Hordijk, P
Uges, DRA
Smit, A
机构：
[1] State Univ Hosp Groningen, Dept Internal Med, NL-9713 EZ Groningen, Netherlands
[2] Psychiat Hosp Dennenoord, Zuidlaren, Netherlands
[3] State Univ Hosp Groningen, Dept Pharm, Groningen, Netherlands
来源：
NETHERLANDS JOURNAL OF MEDICINE | 1998年 / 52卷 / 01期
关键词：
clozapine; agranulocytosis; granulocyte colony stimulating factor;
D O I：
10.1016/S0300-2977(97)00074-0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 46-year-old woman is described with a clozapine-induced agranulocytosis. She was treated with a broad-spectrum antibiotic and supportive care was provided with granulocyte colony-stimulating factor (G-CSF). Immune-mediated mechanisms of clozapine-induced agranulocytosis and the role of haematopoietic growth factors are discussed. (C) 1998 Elsevier Science B.V.
引用
收藏
页码：26 / 29
页数：4
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