Anti-Tobacco Mosaic Virus Isocoumarins from the Leaves of Nicotiana tabacum

被引：4

作者：

Wang, Yuede ^{[1
]}

Wang, Xinlin ^{[2
]}

Zhu, Long ^{[2
]}

Zhang, Tiandong ^{[2
]}

Zhou, Kun ^{[1
]}

Dong, Wei ^{[1
]}

Hu, Wei-Yao ^{[1
]}

Li, Yinke ^{[1
]}

Yang, Guangyu ^{[2
]}

Min, Zhou ^{[1
,2
]}

Hu, Qiufen ^{[1
]}

机构：

[1] Yunnan Minzu Univ, State Ethn Affairs Commiss & Minist Educ, Key Lab Chem Ethn Med Resources, Kunming 650031, Peoples R China

[2] China Tobacco Yunnan Ind Co Ltd, Ctr Technol, Kunming 650000, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2016年 / 52卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Nicotiana tabacum; isocoumarins; anti-tobacco mosaic virus activities; PHENOLIC-COMPOUNDS; ORIENTAL TOBACCO; DERIVATIVES; ROOTS; STEMS;

D O I：

10.1007/s10600-016-1598-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new isocoumarins, tabaisocoumarins D and E (1 and 2), together with two known isocoumarins (3 and 4), were isolated from the leaves of Nicotiana tabacum. The structures of 1-4 were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1-4 were also tested for their anti-tobacco mosaic virus (anti-TMV) activities. Compounds 1-4 exhibited anti-TMV activities with inhibition rates in the range of 11.2-17.5%.

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收藏

页码：218 / 221

页数：4

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