Characterization of FOX-3, an AmpC-type plasmid-mediated β-lactamase from an Italian isolate of Klebsiella oxytoca

被引:0
作者
Marchese, A
Arlet, G
Schito, GC
Lagrange, PH
Philippon, A
机构
[1] Hop St Louis, Microbiol Serv, F-75475 Paris 10, France
[2] Ist Microbiol, I-16132 Genoa, Italy
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中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Klebsiella oxytoca 1731, which showed a wide spectrum of resistance to beta-lactams, including cefoxitin, was isolated in 1994 from a patient in Genoa, Italy. This strain contained a plasmid-mediated AmpC beta-lactamase with a pI of 7.25, Sequencing of the corresponding DNA of K. oxytoca 1731 revealed 96 and 97% identities of the deduced amino acid sequence with FOX-1 and FOX-2, respectively.
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页码:464 / 467
页数:4
相关论文
共 28 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]   BASIC LOCAL ALIGNMENT SEARCH TOOL [J].
ALTSCHUL, SF ;
GISH, W ;
MILLER, W ;
MYERS, EW ;
LIPMAN, DJ .
JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) :403-410
[3]  
ARLET G, 1995, FEMS MICROBIOL LETT, V134, P203, DOI 10.1111/j.1574-6968.1995.tb07938.x
[4]   Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance [J].
Bauernfeind, A ;
Stemplinger, I ;
Jungwirth, R ;
Giamarellou, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (01) :221-224
[5]   Comparative characterization of the cephamycinase bla(CMY-1) gene and its relationship with other beta-lactamase genes [J].
Bauernfeind, A ;
Stemplinger, I ;
Jungwirth, R ;
Wilhelm, R ;
Chong, Y .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (08) :1926-1930
[6]   A novel class C beta-lactamase (FOX-2) in Escherichia coli conferring resistance to cephamycins [J].
Bauernfeind, A ;
Wagner, S ;
Jungwirth, R ;
Schneider, I ;
Meyer, D .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (09) :2041-2046
[7]   Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the loss of an outer membrane protein [J].
Bradford, PA ;
Urban, C ;
Mariano, N ;
Projan, SJ ;
Rahal, JJ ;
Bush, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (03) :563-569
[8]   A FUNCTIONAL CLASSIFICATION SCHEME FOR BETA-LACTAMASES AND ITS CORRELATION WITH MOLECULAR-STRUCTURE [J].
BUSH, K ;
JACOBY, GA ;
MEDEIROS, AA .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (06) :1211-1233
[9]   Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 beta-lactamase (LAT-2) [J].
Gazouli, M ;
Tzouvelekis, LS ;
Prinarakis, E ;
Miriagou, V ;
Tzelepi, E .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (07) :1736-1740
[10]  
HIGGINS DG, 1992, COMPUT APPL BIOSCI, V8, P189