Mapping Local pH in Live Cells Using Encapsulated Fluorescent SERS Nanotags

被引：151

作者：

Pallaoro, Alessia ^{[1
]}

Braun, Gary B. ^{[1
]}

Reich, Norbert. O. ^{[1
]}

Moskovits, Martin ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

SMALL | 2010年 / 6卷 / 05期

基金：

美国国家科学基金会;

关键词：

intracellular pH; nanoparticles; nanotags; surface-enhanced raman spectroscopy; SURFACE-ENHANCED RAMAN; PLASMID DNA; SCATTERING; SILVER; ACID; DELIVERY; PROBE; NANOPARTICLES; ENDOCYTOSIS; ENDOSOMES;

D O I：

10.1002/smll.200901893

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Small Ag clusters incorporating both the pH-sensitive Raman probe molecule 4-mercaptobenzoic acid and a fluorescent dye are used to determine the local pH from the spatially mapped surface-enhanced Raman spectra correlated with the fluorescence, allowing simultaneous single-particle tracking and local pH sensing. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：618 / 622

页数：5

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