A room temperature cyanation of (hetero) aromatic chlorides by an air stable nickel(II) XantPhos precatalyst and Zn(CN)2

被引：24
作者：
Beattie, D. Dawson [1 ]
Schareina, Thomas [2 ]
Beller, Matthias [2 ]
机构：
[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada
[2] Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29A, D-18059 Rostock, Germany
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 20期
基金：
加拿大自然科学与工程研究理事会;
关键词：
PALLADIUM-CATALYZED CYANATION; GENERATED IN-SITU; HALIDES; COMPLEXES; HYDROCYANATION; MECHANISM; LIGAND;
D O I：
10.1039/c7ob00892a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A methodology for the synthesis of (hetero) aromatic nitriles from aryl chlorides at room temperature has been developed. This methodology uses an air and moisture stable nickel(II) XantPhos precatalyst and Zn(CN)(2) as the cyanide (CN-) source.
引用
收藏
页码：4291 / 4294
页数：4
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