Dextran fouling of polyethersulfone ultrafiltration membranes - Causes, extent and consequences

In a recent paper [Susanto, Ulbricht, J. Membr. Sci. 266 (2005) 132], we showed that dextran does foul polyethersulfone (PES) ultrafiltration (UF) membranes by contact of the solution with the membrane surface without flux through the membrane. In this work, dextran fouling was visualized using atomic force microscopy (AFM) and quantified by ATR-IR spectroscopy and by the mass balance in simultaneous diffusion-adsorption measurements (SDAM). Good correlations have been found between the water flux reduction due to dextran adsorption and the quantitative data for bound dextran on the PES membranes. Further, a pronounced effect of dextran size on adsorptive membrane fouling was identified. Contact angle and zeta potential measurements with non-porous films, where solute entrapment in pores can be ruled out, gave additional clear evidence for dextran binding on the PES surface. Complementary data for adsorption and fouling of porous membranes and non-porous films by the protein myoglobin indicated that the larger fouling tendency for protein than for dextran is due to a higher surface coverage of PES by the adsorbed biomacromolecule layer. Data for batch UF confirm the conclusions from the static contact experiments because significant fouling is observed for PES membranes (more severe for myoglobin than for dextrans), while no fouling is seen for a cellulose-based UF membrane with the same nominal cut-off. Finally, two mechanisms for the attractive PES-dextran interaction - multiple hydrogen bonding involving the SO2 groups of PES and "surface dehydration" of the relatively hydrophobic PES - are discussed. (C) 2007 Elsevier B.V. All rights reserved.