Methylglyoxal: A New Weapon against Staphylococcal Wound Infections?

被引：6

作者：

Fidaleo, Marco ^{[2
]}

Zuorro, Antonio ^{[1
]}

Lavecchia, Roberto ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dept Chem Engn, I-00184 Rome, Italy

[2] Univ Roma La Sapienza, Dept Cellular & Dev Biol, I-00185 Rome, Italy

来源：

CHEMISTRY LETTERS | 2010年 / 39卷 / 04期

关键词：

MANUKA; HONEYS;

D O I：

10.1246/cl.2010.322

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Methylglyoxal (MG), a phytochemical present in some New Zealand honeys, was found to possess bactericidal activity against S. aureus and a methicillin-resistant strain of S. epidermidis. The MIC and MBC values were 1.05 and 2.11 mM, respectively. Inclusion of MG in a hydrogel resulted in an active and stable preparation suitable for treating wound or burn infections.

引用

页码：322 / 323

页数：2

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