99mTc-MDP SPECT/CT Demonstrating Extraosseous Periarticular Amyloid Deposits in Primary Systemic Amyloidosis Associated With Multiple Myeloma

被引：7

作者：

Agarwal, Krishan Kant ^{[1
]}

Karunanithi, Sellam ^{[1
]}

Roy, Shambo Guha ^{[1
]}

Bal, Chandrasekhar ^{[1
]}

Kumar, Rakesh ^{[1
]}

机构：

[1] All India Inst Med Sci, Dept Nucl Med, New Delhi, India

来源：

CLINICAL NUCLEAR MEDICINE | 2015年 / 40卷 / 02期

关键词：

primary systemic amyloidosis; Tc-99m-MDP; SPECT/CT; extraosseous; multiple myeloma; SOFT-TISSUE UPTAKE; DIPHOSPHONATE;

D O I：

10.1097/RLU.0000000000000593

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Amyloidosis is a rare disorder characterized by variable extracellular accumulation of a complex substance consisting of proteinaceous fibrils (amyloid fibrils) and nonfibrillar glycoprotein or amyloid P component. We present a case of a primary systemic amyloidosis associated with multiple myeloma in a 48-year-old woman whose Tc-99m-MDP SPECT/CT study revealed extraosseous periarticular uptake in amyloid deposits with no abnormal focal tracer uptake in the bone.

引用

页码：189 / 190

页数：2

共 8 条

[1] NEW FRONTIERS IN THE STUDY OF AMYLOIDOSIS [J].

COHEN, AS ;

SKINNER, M .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (08) :542-543

[2] Utility of 18F-FDG PET(/CT) in patients with systemic and localized amyloidosis [J].

Glaudemans, Andor W. J. M. ;

Slart, Riemer H. J. A. ;

Noordzij, Walter ;

Dierckx, Rudi A. J. O. ;

Hazenberg, Bouke P. C. .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 (07) :1095-1101

[3] SOFT-TISSUE UPTAKE OF TC-99M DIPHOSPHONATE IN SYSTEMIC AL AMYLOIDOSIS [J].

JANSSEN, S ;

VANRIJSWIJK, MH ;

PIERS, DA ;

DEJONG, GMT .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1984, 9 (12) :538-541

[4] SOFT-TISSUE UPTAKE OF TC-99M-DIPHOSPHONATE AND TC-99M-PYROPHOSPHATE IN AMYLOIDOSIS [J].

JANSSEN, S ;

PIERS, DA ;

VANRIJSWIJK, MH ;

MEIJER, S ;

MANDEMA, E .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1990, 16 (8-10) :663-670

[5] 18F-FDG PET/CT in patients with amyloid light-chain amyloidosis: case-series and literature review [J].

Mekinian, Arsene ;

Jaccard, Arnaud ;

Soussan, Michael ;

Launay, David ;

Berthier, Sabine ;

Federici, Laure ;

Lefevre, Guillaume ;

Valeyre, Dominique ;

Dhote, Robin ;

Fain, Olivier .

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2012, 19 (02) :94-98

[6] BONE-SCAN IN SYSTEMIC AMYLOIDOSIS [J].

ROSELLO, R ;

LOMENA, F ;

PONS, F ;

GRAU, M ;

SOLE, M ;

PARE, C ;

CATAFAU, A ;

HERRANZ, R .

NUCLEAR MEDICINE COMMUNICATIONS, 1988, 9 (11) :879-890

[7] Absent skeletal uptake of 99mTc-hydroxymethylene diphosphonate in the presence of AL-type amyloidosis associated with multiple myeloma [J].

Sasaki, Tomoaki ;

Okizaki, Atsutaka ;

Takahashi, Koji ;

Mineta, Masayuki ;

Nagasawa, Kenichi ;

Fujimoto, Yasuomi ;

Kohda, Kyuhei ;

Aburano, Tamio .

JAPANESE JOURNAL OF RADIOLOGY, 2011, 29 (08) :595-597

[8]

WORSLEY DF, 1993, J NUCL MED, V34, P1612

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