Factors Associated With Mortality Among the COVID-19 Patients Treated at Gulu Regional Referral Hospital: A Retrospective Study

被引:11
作者
Baguma, Steven [1 ,2 ]
Okot, Christopher [1 ,2 ]
Alema, Nelson Onira [1 ,3 ]
Apiyo, Paska [1 ,2 ]
Layet, Paska [1 ,4 ]
Acullu, Denis [1 ,5 ]
Oloya, Johnson Nyeko [1 ]
Ochula, Denis [1 ,6 ]
Atim, Pamela [1 ,7 ]
Olwedo, Patrick Odong [1 ,8 ]
Okot, Smart Godfrey [1 ,9 ]
Oyat, Freddy Wathum Drinkwater [1 ]
Oola, Janet [1 ,10 ]
Ikoona, Eric Nzirakaindi [11 ]
Aloyo, Judith [1 ,12 ]
Kitara, David Lagoro [1 ,13 ]
机构
[1] Uganda Med Assoc UMA, UMA Acholi Branch, Gulu, Uganda
[2] Gulu Reg Referral Hosp, Gulu, Uganda
[3] Gulu Univ, Dept Anat, Fac Med, Gulu, Uganda
[4] St Marys Hosp, Dept Med, Lacor, Gulu, Uganda
[5] Aga Kan Hosp, Mombasa, Kenya
[6] Lamwo Dist Local Govt, Dist Hlth Off, Padibe, Uganda
[7] St Josephs Hosp, Kitgum, Uganda
[8] Amuru Dist Local Govt, Dist Hlth Off, Amuru, Uganda
[9] Ambrosoli Hosp, Kalongo, Uganda
[10] Nwoya Dist Local Govt, Dist Hlth Off, Anaka, Uganda
[11] ICAP Columbia Univ, Freetown, Sierra Leone
[12] Rhites N, Acholi, Gulu, Uganda
[13] Gulu Univ, Dept Surg, Fac Med, Gulu, Uganda
关键词
COVID-19; Gulu Hospital; mortality; comorbidities; female; MORBIDITY;
D O I
10.3389/fpubh.2022.841906
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
BackgroundThe advent of the novel coronavirus disease 2019 (COVID-19) has caused millions of deaths worldwide. As of December 2021, there is inadequate data on the outcome of hospitalized patients suffering from COVID-19 in Africa. This study aimed at identifying factors associated with hospital mortality in patients who suffered from COVID-19 at Gulu Regional Referral Hospital in Northern Uganda from March 2020 to October 2021. MethodsThis was a single-center, retrospective cohort study in patients hospitalized with confirmed SARS-CoV-2 at Gulu Regional Referral Hospital in Northern Uganda. Socio-demographic characteristics, clinical presentations, co-morbidities, duration of hospital stay, and treatments were analyzed, and factors associated with the odds of mortality were determined. ResultsOf the 664 patients treated, 661 (99.5%) were unvaccinated, 632 (95.2%) recovered and 32 (4.8%) died. Mortality was highest in diabetics 11 (34.4%), cardiovascular diseases 12 (37.5%), hypertensives 10 (31.3%), females 18 (56.3%), >= 50-year-olds 19 (59.4%), no formal education 14 (43.8%), peasant farmers 12 (37.5%) and those who presented with difficulty in breathing/shortness of breath and chest pain 32 (100.0%), oxygen saturation (SpO(2)) at admission <80 4 (12.5%), general body aches and pains 31 (96.9%), tiredness 30 (93.8%) and loss of speech and movements 11 (34.4%). The independent factors associated with mortality among the COVID-19 patients were females AOR = 0.220, 95%CI: 0.059-0.827; p = 0.030; Diabetes mellitus AOR = 9.014, 95%CI: 1.726-47.067; p = 0.010; Ages of 50 years and above AOR = 2.725, 95%CI: 1.187-6.258; p = 0.018; tiredness AOR = 0.059, 95%CI: 0.009-0.371; p < 0.001; general body aches and pains AOR = 0.066, 95%CI: 0.007-0.605; p = 0.020; loss of speech and movement AOR = 0.134, 95%CI: 0.270-0.660; p = 0.010 and other co-morbidities AOR = 6.860, 95%CI: 1.309-35.957; p = 0.020. ConclusionThe overall Gulu Regional Hospital mortality was 32/664 (4.8%). Older age, people with diabetics, females, other comorbidities, severe forms of the disease, and those admitted to HDU were significant risk factors associated with hospital mortality. More efforts should be made to provide "additional social protection" to the most vulnerable population to avoid preventable morbidity and mortality of COVID-19 in Northern Uganda.
引用
收藏
页数:11
相关论文
共 50 条
[41]   Echocardiographic Abnormalities as Independent Prognostic Factors of In-Hospital Mortality among COVID-19 Patients [J].
Pishgahi, Mehdi ;
Toudeshki, Kimia Karimi ;
Safari, Saeed ;
Yousefifard, Mahmoud .
ARCHIVES OF ACADEMIC EMERGENCY MEDICINE, 2021, 9 (01)
[42]   Factors associated with mortality in critically ill patients with COVID-19 [J].
de Almeida, Rafaela dos Santos Charao ;
Klafke, Andre ;
Garbini, Andresa Fontoura ;
Carazai, Daniela dos Reis ;
dos Santos, Fernanda Costa ;
Lutkmeier, Raquel ;
Baldon, Veridiana .
REVISTA DE EPIDEMIOLOGIA E CONTROLE DE INFECCAO, 2022, 12 (04)
[43]   Predictors of intubation and mortality in COVID-19 patients: a retrospective study [J].
Cena, Tiziana ;
Cammarota, Gianmaria ;
Azzolina, Danila ;
Barini, Michela ;
Bazzano, Simona ;
Zagaria, Domenico ;
Negroni, Davide ;
Castello, Luigi ;
Carriero, Alessandro ;
Della Corte, Francesco ;
Vaschetto, Rosanna .
JOURNAL OF ANESTHESIA ANALGESIA AND CRITICAL CARE, 2021, 1 (01)
[44]   Regional differences in triage decisions affect hospital mortality among frail COVID-19 patients in the COvid MEdicaTion study [J].
Minnema, Julia ;
Sablerolles, Roos ;
van Kempen, Janneke ;
van der Kuy, Hugo ;
Polinder-Bos, Harmke ;
van de Loo, Bob ;
Versmissen, Jorie ;
Haaksma, Miriam L. ;
Lafeber, Melvin ;
Faes, Miriam C. ;
COMET Res Team .
BMC INFECTIOUS DISEASES, 2025, 25 (01)
[45]   Risk factors for mortality in COVID-19 patients in a community teaching hospital [J].
Andrade, Justin A. ;
Muzykovsky, Karina ;
Truong, James .
JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (05) :3184-3193
[46]   Factors in Relation with in-Hospital Mortality in Geriatric Patients with COVID-19 [J].
Emektar, Emine ;
Koc, Filiz ;
Goktas, Emine Firat ;
Dagar, Seda ;
Uzunosmanoglu, Huseyin .
CYPRUS JOURNAL OF MEDICAL SCIENCES, 2022, 7 (03) :330-336
[47]   COVID-19 Vaccine Effectiveness at a Referral Hospital in Northern Peru: A Retrospective Cohort Study [J].
Valladares-Garrido, Mario J. ;
Zena-Nanez, Sandra ;
Ichiro Peralta, C. ;
Puicon-Suarez, Jacqueline B. ;
Diaz-Velez, Cristian ;
Failoc-Rojas, Virgilio E. .
VACCINES, 2022, 10 (05)
[48]   Predictors of hospital mortality among patients with COVID-19 in Tehran, Iran [J].
Esfahanian, Fatemeh ;
SeyedAlinaghi, SeyedAhmad ;
Janfaza, Nazanin ;
Tantuoyir, Marcarious M. .
SAGE OPEN MEDICINE, 2021, 9
[49]   A Retrospective Cohort Study of Clinical Factors Associated with Transitions of Care among COVID-19 Patients [J].
Swearingen, Dennis ;
Boverman, Gregory ;
Tgavalekos, Kristen ;
Noren, David P. ;
Ravindranath, Shreyas ;
Ghosh, Erina ;
Xu, Minnan ;
Wondrely, Lisa ;
Thompson, Pam ;
Cowden, J. David ;
Antonescu, Corneliu .
JOURNAL OF CLINICAL MEDICINE, 2021, 10 (19)
[50]   Predictors of In-Hospital Mortality in Older Patients With COVID-19: The COVIDAge Study [J].
Mendes, Aline ;
Serratrice, Christine ;
Herrmann, Francois R. ;
Genton, Laurence ;
Perivier, Samuel ;
Scheffler, Max ;
Fassier, Thomas ;
Huber, Philippe ;
Jacques, Marie-Claire ;
Prendki, Virginie ;
Roux, Xavier ;
Di Silvestro, Katharine ;
Trombert, Veronique ;
Harbarth, Stephan ;
Gold, Gabriel ;
Graf, Christophe E. ;
Zekry, Dina .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2020, 21 (11) :1546-+