Vitamin E and Risk of Cardiovascular Diseases: A Review of Epidemiologic and Clinical Trial Studies

被引：52

作者：

Cordero, Zorabel ^{[1
]}

Drogan, Dagmar ^{[1
]}

Weikert, Cornelia ^{[1
]}

Boeing, Heiner ^{[1
]}

机构：

[1] German Inst Human Nutr Potsdam Rehbrucke, Dept Epidemiol, D-14558 Nuthetal, Germany

来源：

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION | 2010年 / 50卷 / 05期

关键词：

diet; supplementation; blood concentration; vitamin E; prospective study; randomized clinical trial; meta-analysis; CORONARY-HEART-DISEASE; TOCOPHEROL-MEDIATED PEROXIDATION; DIETARY ANTIOXIDANT VITAMINS; BETA-CAROTENE SUPPLEMENTS; FREE-RADICAL INTERACTION; LOW-DENSITY-LIPOPROTEIN; ALPHA-TOCOPHEROL; GAMMA-TOCOPHEROL; MYOCARDIAL-INFARCTION; SERUM CONCENTRATIONS;

D O I：

10.1080/10408390802304230

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Cardiovascular diseases are the leading cause of worldwide mortality. There is strong epidemiologic evidence for a beneficial effect of vitamin E on cardiovascular disease risk. However, conflicting results have been reported by intervention studies. To assess the potential benefit of vitamin E intake on the risk of cardiovascular diseases, fifty-nine published reports from observational studies, retrospective and prospective, randomised clinical trials, meta-analyses as well as pooling analyses were reviewed. The paper provides a detailed discussion about design, quality and limitations of these studies with regard to the evidence of the hypothesized relationship between vitamin E and cardiovascular diseases.

引用

页码：420 / 440

页数：21

共 168 条

[1]

[Anonymous], DIET REF INT VIT C V

[2] Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States [J].

Ascherio, A ;

Rimm, EB ;

Hernán, MA ;

Giovannucci, E ;

Kawachi, I ;

Stampfer, MJ ;

Willett, WC .

ANNALS OF INTERNAL MEDICINE, 1999, 130 (12) :963-970

[3] CORRELATIONS OF VITAMIN-A AND VITAMIN-E INTAKES WITH THE PLASMA-CONCENTRATIONS OF CAROTENOIDS AND TOCOPHEROLS AMONG AMERICAN MEN AND WOMEN [J].

ASCHERIO, A ;

STAMPFER, MJ ;

COLDITZ, GA ;

RIMM, EB ;

LITIN, L ;

WILLETT, WC .

JOURNAL OF NUTRITION, 1992, 122 (09) :1792-1801

[4] Antioxidant vitamins in the prevention of cardiovascular disease: a systematic review [J].

Asplund, K .

JOURNAL OF INTERNAL MEDICINE, 2002, 251 (05) :372-392

[5] Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering [J].

Azen, SP ;

Qian, DJ ;

Mack, WJ ;

Sevanian, A ;

Selzer, RH ;

Liu, CR ;

Liu, CH ;

Hodis, HN .

CIRCULATION, 1996, 94 (10) :2369-2372

[6] VITAMIN-E - A SENSOR AND AN INFORMATION TRANSDUCER OF THE CELL OXIDATION-STATE [J].

AZZI, A ;

BOSCOBOINIK, D ;

MARILLEY, D ;

OZER, NK ;

STAUBLE, B ;

TASINATO, A .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1995, 62 (06) :1337-1346

[7] γ-Tocopherol as a possible marker for nutrition-related risk:: results from four National Diet and Nutrition Surveys in Britain [J].

Bates, CJ ;

Mishra, GD ;

Prentice, A .

BRITISH JOURNAL OF NUTRITION, 2004, 92 (01) :137-150

[8] Re-evaluation of the relative potency of synthetic and natural α-tocopherol:: experimental and clinical observations [J].

Blatt, DH ;

Pryor, WA ;

Mata, JE ;

Rodriguez-Proteau, R .

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2004, 15 (07) :380-395

[9] VALIDATION OF A SELF-ADMINISTERED DIET HISTORY QUESTIONNAIRE USING MULTIPLE DIET RECORDS [J].

BLOCK, G ;

WOODS, M ;

POTOSKY, A ;

CLIFFORD, C .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1990, 43 (12) :1327-1335

[10]

BLOCK G, 1995, AM J CLIN NUTR, V62, P1517

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