The surface layer of binary Al-Zn alloy specimen, ever after a long time aging, remains softer than the interior when the specimens are age-hardened at around room temperature after quenching from high temperature. In this study, effects of the soft surface layer on the fatigue strength of Al-Zn alloys were studied under repeated tensile loading. Vickers microharhness test revealed that there existed less hardened region in the vicinity of grain boundary and specimens surface, and that the region extends 50 to 100 mu m from the surface inward. From the plot of the stress amplitude against the number of cycles to failure, it is concluded that the presence of less hardened surface layer increases fatigue resistance of age-hardened AI-Zn alloys containing 8 to 16 mass%Zn under the repeated tensile loading.