In vitro activity of linezolid against slowly growing nontuberculous mycobacteria

被引：63

作者：

Brown-Elliott, BA ^{[1
]}

Crist, CJ ^{[1
]}

Mann, LB ^{[1
]}

Wilson, RW ^{[1
]}

Wallace, RJ ^{[1
]}

机构：

[1] Univ Texas Hlth Ctr, Dept Microbiol, Tyler, TX 75708 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 05期

关键词：

D O I：

10.1128/AAC.47.5.1736-1738.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

MICs of linezolid in broth microdilutions were tested against 341 slowly growing nontuberculous mycobacteria (NTM) belonging to 15 species. The proposed linezolid susceptibility MICs for all Mycobacterium marinum, Mycobacterium szulgai, Mycobacterium kansasii, Mycobacterium malmoense, and Mycobacterium xenopi isolates and for 90% of Mycobacterium gordonae and Mycobacterium triplex isolates were less than or equal to8 mug/ml. Linezolid has excellent therapeutic potential against most species of NTM.

引用

页码：1736 / 1738

页数：3

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