Tunable optofluidic microlens through active pressure control of an air-liquid interface

被引:47
作者
Shi, Jinjie [1 ]
Stratton, Zak [1 ]
Lin, Sz-Chin Steven [1 ]
Huang, Hua [1 ]
Huang, Tony Jun [1 ]
机构
[1] Penn State Univ, Dept Engn Sci & Mech, University Pk, PA 16802 USA
基金
美国国家科学基金会;
关键词
Optofluidic; Tunable lens; Microfluidics; Air-liquid interface; WAVE-GUIDES; MANIPULATION; LENS; CELLS; MICROPARTICLES; CHIP;
D O I
10.1007/s10404-009-0548-9
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
We demonstrate a tunable in-plane optofluidic microlens with a 9x light intensity enhancement at the focal point. The microlens is formed by a combination of a tunable divergent air-liquid interface and a static polydimethylsiloxane lens, and is fabricated using standard soft lithography procedures. When liquid flows through a straight channel with a side opening (air reservoir) on the sidewall, the sealed air in the side opening bends into the liquid, forming an air-liquid interface. The curvature of this air-liquid interface can be conveniently and predictably controlled by adjusting the flow rate of the liquid stream in the straight channel. This change in the interface curvature generates a tunable divergence in the incident light beam, in turn tuning the overall focal length of the microlens. The tunability and performance of the lens are experimentally examined, and the experimental data match well with the results from a ray-tracing simulation. Our method features simple fabrication, easy operation, continuous and rapid tuning, and a large tunable range, making it an attractive option for use in lab-on-a-chip devices, particularly in microscopic imaging, cell sorting, and optical trapping/manipulating of microparticles.
引用
收藏
页码:313 / 318
页数:6
相关论文
共 50 条
[41]   Enhanced sodium absorption in middle ear epithelial cells cultured at air-liquid interface [J].
Portier, F ;
Kania, R ;
Planès, C ;
Hsu, WC ;
Couette, S ;
Huy, PTB ;
Herman, P .
ACTA OTO-LARYNGOLOGICA, 2005, 125 (01) :16-22
[42]   An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing [J].
Braakhuis, Hedwig M. ;
He, Ruiwen ;
Vandebriel, Rob J. ;
Gremmer, Eric R. ;
Zwart, Edwin ;
Vermeulen, Jolanda P. ;
Fokkens, Paul ;
Boere, John ;
Gosens, Ilse ;
Cassee, Flemming R. .
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2020, (159)
[43]   Effects of Female Sex Hormones on Susceptibility to HSV-2 in Vaginal Cells Grown in Air-Liquid Interface [J].
Lee, Yung ;
Dizzell, Sara E. ;
Leung, Vivian ;
Nazli, Aisha ;
Zahoor, Muhammad A. ;
Fichorova, Raina N. ;
Kaushic, Charu .
VIRUSES-BASEL, 2016, 8 (09)
[44]   A bionic controllable strain membrane for cell stretching at air-liquid interface inspired by papercutting [J].
Li, Yuanrong ;
Xie, Mingjun ;
Lv, Shang ;
Sun, Yuan ;
Li, Zhuang ;
Gu, Zeming ;
He, Yong .
INTERNATIONAL JOURNAL OF EXTREME MANUFACTURING, 2023, 5 (04)
[45]   In vitro toxicity testing of cigarette smoke based on the air-liquid interface exposure: A review [J].
Li, Xiang .
TOXICOLOGY IN VITRO, 2016, 36 :105-113
[46]   Reparation of an Inflamed Air-Liquid Interface Cultured A549 Cells with Nebulized Nanocurcumin [J].
Altube, Maria Julia ;
Caimi, Lilen Ivonne ;
Huck-Iriart, Cristian ;
Morilla, Maria Jose ;
Romero, Eder Lilia .
PHARMACEUTICS, 2021, 13 (09)
[47]   A mobile air-liquid interface exposure system optimized for outdoor toxicity testing of aerosols [J].
Juarez-Facio, Ana Teresa ;
Introna, Micol ;
Gustavsson, Sven ake ;
Attergren, Max ;
Lindwall, Martin ;
Olofsson, Ulf ;
Steimer, Sarah Sulamith ;
Elihn, Karine .
AEROSOL SCIENCE AND TECHNOLOGY, 2025, 59 (02) :214-226
[48]   Determinative Factors of Competitive Advantage between Aerobic Bacteria for Niches at the Air-Liquid Interface [J].
Yamamoto, Kyosuke ;
Haruta, Shin ;
Kato, Souichiro ;
Ishii, Masaharu ;
Igarashi, Yasuo .
MICROBES AND ENVIRONMENTS, 2010, 25 (04) :317-320
[49]   Gravity-Driven Air-Liquid Interface Flexible Sensor for Human Motion Detection [J].
Zhuang, Zhenqian ;
Ding, Ke ;
Zhong, Hailing ;
Shen, Lan ;
Zhang, Zuowen .
SMALL, 2025,
[50]   Air-liquid interface cell culture: From airway epithelium to the female reproductive tract [J].
Chen, Shuai ;
Schoen, Jennifer .
REPRODUCTION IN DOMESTIC ANIMALS, 2019, 54 :38-45