HIV HGM biobank as a research platform for paediatric infectious diseases and COVID-19 pandemic

被引:1
作者
Irene, Consuegra [1 ,2 ]
Elba, Mauleon [1 ,2 ]
Luis Jimenez, Jose [1 ,2 ,3 ]
Jose Mellado, Maria [4 ]
Angeles Munoz-Fernandez, Maria [1 ,2 ,5 ,6 ]
机构
[1] Inst Invest Sanitaria Gregorio Maranon IiSGM, Madrid, Spain
[2] HIV HGM BioBank, Madrid, Spain
[3] Plataforma Lab IiSGM, Madrid, Spain
[4] Univ La Paz, Infect & Trop Dis Dept Hosp, Gen Pediat, Madrid, Spain
[5] Lab InmunoBiol Mol HGUGM, Madrid, Spain
[6] Hosp Gen Univ Gregorio Maranon, Immunol Sect, C Dr Esquerdo 46, Madrid 28007, Spain
关键词
BioBank; HIV; COVID-19; Paediatric; Pandemics; Research infrastructure; CARE; OUTBREAK; DENGUE; IMPACT;
D O I
10.1186/s12981-022-00448-1
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Aim The initial cases of COVID-19 appeared in December 2019 and Spain was one of the most affected countries during the first wave (March to June). Since then, HIV HGM BioBank has been restructured as an established Paediatrics and Adults HIV_COVID-19 BioBank that aims at the long-term storage of samples obtained from not only HIV-1, but also from COVID-19 patients and HIV-1_COVID-19 coinfected patients. Methods HIV HGM BioBank holds high quality biological samples from newborns, children, adolescents and adults with their associated clinical data. Research groups trying to establish large networks focused on research on specific clinical problems in epidemiology, biology, routes of transmission and therapies, are potential users of the clinical samples and of associated data of HIV-1_COVID-19 HGM BioBank. Results The HIV HGM BioBank is an academic and ethical enterprise complying with all the legal regulatory rules to provide service to the society. HIV_COVID-19 HGM BioBank has been repurposed to offer an important resource for global research of COVID-19 in newborns, children, adolescents, adults and elders to study the biological effect of the pandemic. Conclusion Herein, we present a description of how HIV HGM BioBank has rapidly become an indispensable structure in modern biomedical research, including COVID-19 research. Keypoints Biobanks are essential platforms for the development of personalized medicine, even more so in pediatric diseases, including those of infectious origin. The possibility of having collections of excellent quality and with all the ethical and legal requirements is even more relevant in pandemic situations.
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