Assessing food allergy risks from residual peanut protein in highly refined vegetable oil

被引:16
作者
Blom, W. Marty [1 ]
Kruizinga, Astrid G. [1 ]
Rubingh, Carina M. [1 ]
Remington, Ben C. [1 ]
Crevel, Rene W. R. [2 ]
Houben, Geert F. [1 ]
机构
[1] Netherlands Org Appl Sci Res TNO, Zeist, Netherlands
[2] Unilever, SEAC, Colworth Sci Pk, Sharnbrook, Beds, England
关键词
Allergen risk assessment; Food allergy; Precautionary allergen labeling; Refined peanut oil; Refined vegetable oils; Unintended peanut protein; MODEL;
D O I
10.1016/j.fct.2017.05.072
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Refined vegetable oils including refined peanut oil are widely used in foods. Due to shared production processes, refined non-peanut vegetable oils can contain residual peanut proteins. We estimated the predicted number of allergic reactions to residual peanut proteins using probabilistic risk assessment applied to several scenarios involving food products made with vegetable oils. Variables considered were: a) the estimated production scale of refined peanut oil, b) estimated cross-contact between refined vegetable oils during production, c) the proportion of fat in representative food products and d) the peanut protein concentration in refined peanut oil. For all products examined the predicted risk of objective allergic reactions in peanut-allergic users of the food products was extremely low. The number of predicted reactions ranged depending on the model from a high of 3 per 1000 eating occasions (Weibull) to no reactions (LogNormal). Significantly, all reactions were predicted for allergen intakes well below the amounts reported for the most sensitive indiVidual described in the clinical literature. We conclude that the health risk from cross-contact between vegetable oils and refined peanut oil is negligible. None of the food products would warrant precautionary labelling for peanut according to the VITAL programme of the Allergen Bureau. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:306 / 313
页数:8
相关论文
共 29 条
  • [1] Allergen reference doses for precautionary labeling (VITAL 2.0): Clinical implications
    Allen, Katrina J.
    Remington, Benjamin C.
    Baumert, Joseph L.
    Crevel, Rene W. R.
    Houben, Geert F.
    Brooke-Taylor, Simon
    Kruizinga, Astrid G.
    Taylor, Steve L.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (01) : 156 - 164
  • [2] How much is too much? Threshold dose distributions for 5 food allergens
    Ballmer-Weber, Barbara K.
    Fernandez-Rivas, Montserrat
    Beyer, Kirsten
    Defernez, Marianne
    Sperrin, Matthew
    Mackie, Alan R.
    Salt, Louise J.
    Hourihane, Jonathan O'B.
    Asero, Riccardo
    Belohlavkova, Simona
    Kowalski, Marek
    de Blay, Frederic
    Papadopoulos, Nikolaos G.
    Clausen, Michael
    Knulst, Andre C.
    Roberts, Graham
    Popov, Ted
    Sprikkelman, Aline B.
    Dubakiene, Ruta
    Vieths, Stefan
    van Ree, Ronald
    Crevel, Rene
    Mills, E. N. Clare
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (04) : 964 - 971
  • [3] Cochrane Stella Anne, 2013, Clin Transl Allergy, V3, P31, DOI 10.1186/2045-7022-3-31
  • [4] Hazard characterisation in food allergen risk assessment: The application of statistical approaches and the use of clinical data
    Crevel, R. W. R.
    Briggs, D.
    Hefle, S. L.
    Knulst, A. C.
    Taylor, S. L.
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2007, 45 (05) : 691 - 701
  • [5] Development and evolution of risk assessment for food allergens
    Crevel, Rene W. R.
    Baumert, Joseph L.
    Baka, Athanasia
    Houben, Geert F.
    Knulst, Andre C.
    Kruizinga, Astrid G.
    Luccioli, Stefano
    Taylor, Stephen L.
    Madsen, Charlotte B.
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2014, 67 : 262 - 276
  • [6] Allergenicity of refined vegetable oils
    Crevel, RWR
    Kerkhoff, MAT
    Koning, MMG
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2000, 38 (04) : 385 - 393
  • [7] EFSA Panel on Dietetic Products Nutrition and Allergies, 2004, EFSA J, V2, P133
  • [8] EFSA Panel on Dietetic Products Nutrition and Allergies, 2007, EFSA J, V5, P570
  • [9] FEDIOL report, 2009, 09COD018 FEDIOL
  • [10] Consumer attitudes and risks associated with packaged foods having advisory labeling regarding the presence of peanuts
    Hefle, Susan L.
    Furlong, Terence J.
    Niemann, Lynn
    Lemon-Mule, Heather
    Sicherer, Scott
    Taylor, Steve L.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (01) : 171 - 176