共 20 条
A multicentre European registry to evaluate the Direct Flow Medical transcatheter aortic valve system for the treatment of patients with severe aortic stenosis
被引:8
作者:

Naber, Christoph K.
论文数: 0 引用数: 0
h-index: 0
机构:
Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Pyxaras, Stylianos A.
论文数: 0 引用数: 0
h-index: 0
机构:
Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Ince, Hueseyin
论文数: 0 引用数: 0
h-index: 0
机构:
Vivantes Klinikum Friedrichshain & Urban, Berlin, Germany
Univ Klinikum Rostock, Rostock, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Frambach, Peter
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Chirurg Cardiaque & Cardiol Intervent, Luxembourg, Luxembourg Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Colombo, Antonio
论文数: 0 引用数: 0
h-index: 0
机构:
Ist Sci San Raffaele, Intervent Cardiol Unit, Milan, Italy Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Butter, Christian
论文数: 0 引用数: 0
h-index: 0
机构:
Immanuel Klinikum Bernau, Herzzentrum Brandenburg, Bernau, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Gatto, Fernando
论文数: 0 引用数: 0
h-index: 0
机构:
Herzzentrum Saar, Volklingen, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Hink, Ulrich
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Klinikum Mainz, Mainz, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Nickenig, Georg
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Klinikum Bonn, Bonn, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Bruschi, Giuseppe
论文数: 0 引用数: 0
h-index: 0
机构:
Osped Niguarda Ca Granda, Milan, Italy Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Brueren, Guus
论文数: 0 引用数: 0
h-index: 0
机构:
Catharina Hosp, Eindhoven, Netherlands Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Tchetche, Didier
论文数: 0 引用数: 0
h-index: 0
机构:
Clin Pasteur, Toulouse, France Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Den Heijer, Peter
论文数: 0 引用数: 0
h-index: 0
机构:
Amphia Ziekenhuis Hartctr, Cardiol, Breda, Netherlands Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Schillinger, Wolfgang
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Klinikum Gottingen, Gottingen, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Scholtz, Smita
论文数: 0 引用数: 0
h-index: 0
机构:
Ruhr Univ Bochum, Klin Kardiol Herz & Diabet Zentrum NRW, Bad Oeynhausen, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Van der Heyden, Jan
论文数: 0 引用数: 0
h-index: 0
机构:
St Antonius Hosp, Nieuwegein, Netherlands Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Lefevre, Thierry
论文数: 0 引用数: 0
h-index: 0
机构:
Hop Prive Jacques Cartier, Massy, France Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Gilard, Martine
论文数: 0 引用数: 0
h-index: 0
机构:
CHU Brest, Brest, France Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Kuck, Karl-Heinz
论文数: 0 引用数: 0
h-index: 0
机构:
Asklepios Klin St Georg, Hamburg, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Schofer, Joachim
论文数: 0 引用数: 0
h-index: 0
机构:
Albertinen Herzzentrum, Hamburg, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Divchev, Dimitar
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Klinikum Rostock, Rostock, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Baumgartner, Helmut
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Klinikum Munster, Munster, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Asch, Federico
论文数: 0 引用数: 0
h-index: 0
机构:
MedStar Hlth Res Inst, Washington, DC USA Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Wagner, Daniel
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Chirurg Cardiaque & Cardiol Intervent, Luxembourg, Luxembourg Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Latib, Azeem
论文数: 0 引用数: 0
h-index: 0
机构:
Ist Sci San Raffaele, Intervent Cardiol Unit, Milan, Italy Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

De Marco, Federico
论文数: 0 引用数: 0
h-index: 0
机构:
Osped Niguarda Ca Granda, Milan, Italy Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany

Kische, Stephan
论文数: 0 引用数: 0
h-index: 0
机构:
Vivantes Klinikum Friedrichshain & Urban, Berlin, Germany
Univ Klinikum Rostock, Rostock, Germany Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany
机构:
[1] Elisabeth Krankenhaus Essen, Contilia Heart & Vasc Ctr, Klara Kopp Weg 1, D-45138 Essen, Germany
[2] Vivantes Klinikum Friedrichshain & Urban, Berlin, Germany
[3] Univ Klinikum Rostock, Rostock, Germany
[4] Inst Chirurg Cardiaque & Cardiol Intervent, Luxembourg, Luxembourg
[5] Ist Sci San Raffaele, Intervent Cardiol Unit, Milan, Italy
[6] Immanuel Klinikum Bernau, Herzzentrum Brandenburg, Bernau, Germany
[7] Herzzentrum Saar, Volklingen, Germany
[8] Univ Klinikum Mainz, Mainz, Germany
[9] Univ Klinikum Bonn, Bonn, Germany
[10] Osped Niguarda Ca Granda, Milan, Italy
[11] Catharina Hosp, Eindhoven, Netherlands
[12] Clin Pasteur, Toulouse, France
[13] Amphia Ziekenhuis Hartctr, Cardiol, Breda, Netherlands
[14] Univ Klinikum Gottingen, Gottingen, Germany
[15] Ruhr Univ Bochum, Klin Kardiol Herz & Diabet Zentrum NRW, Bad Oeynhausen, Germany
[16] St Antonius Hosp, Nieuwegein, Netherlands
[17] Hop Prive Jacques Cartier, Massy, France
[18] CHU Brest, Brest, France
[19] Asklepios Klin St Georg, Hamburg, Germany
[20] Albertinen Herzzentrum, Hamburg, Germany
[21] Univ Klinikum Rostock, Rostock, Germany
[22] Univ Klinikum Munster, Munster, Germany
[23] MedStar Hlth Res Inst, Washington, DC USA
关键词:
repositionability;
retrievability;
severe aortic valve stenosis;
transcatheter aortic valve implantation;
IMPLANTATION;
REGURGITATION;
DEFINITIONS;
REPLACEMENT;
PROSTHESIS;
EXPERIENCE;
COREVALVE;
D O I:
10.4244/EIJ-D-15-00511
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Aims: Our aim was to assess the clinical outcomes of the Direct Flow Medical Transcatheter Aortic Valve System (DFM-TAVS), when used in routine clinical practice. Methods and results: This is a prospective, open-label, multicentre, post-market registry of patients treated with DFM-TAVS according to approved commercial indications. Echocardiographic and angiographic data were evaluated by an independent core laboratory and adverse events were adjudicated and classified according to VARC-2 criteria by an independent clinical events committee. The primary endpoint was freedom from all-cause mortality at 30 days post procedure. Secondary endpoints included procedural, early safety and efficacy endpoints at 30 days. Two hundred and fifty patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) with the DFM-TAVS were enrolled in 21 European centres. The primary endpoint, freedom from all-cause mortality at 30 days, was met in 98% (245/250) of patients. Device success was 83.8%. Moderate or severe aortic regurgitation was reported in 3% of patients, and none/trace regurgitation in 73% of patients. Post-procedural permanent pacemaker implantation was performed in 30 patients (12.0%). Conclusions: The DFM-TAVS was associated with good short-term outcomes in this real-world registry. The low pacemaker and aortic regurgitation rates confirm the advantages of this next-generation transcatheter heart valve (THV).
引用
收藏
页码:E1413 / E1419
页数:7
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