Poly(vinylidene fluoride)-based film with strong antimicrobial activity

被引：17

作者：

Han, Dong Je ^{[1
,2
,3
]}

Kim, Seonwoo ^{[1
]}

Heo, Hyeon Jun ^{[1
,4
]}

Jin, Chaewon ^{[5
,6
]}

Kim, Jin-young ^{[5
,6
,7
]}

Choi, Hongsoo ^{[5
,6
]}

Park, In Jun ^{[1
]}

Kang, Hong Suk ^{[1
]}

Lee, Sang Goo ^{[1
]}

Lee, Jong-Chan ^{[2
,3
]}

Sohn, Eun-Ho ^{[1
,4
]}

机构：

[1] Korea Res Inst Chem Technol, Interface Mat & Chem Engn Res Ctr, Daejeon 34114, South Korea

[2] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 08826, South Korea

[3] Seoul Natl Univ, Inst Chem Proc, Seoul 08826, South Korea

[4] Univ Sci & Technol, Adv Mat & Chem Engn, Daejeon 34113, South Korea

[5] Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept Robot Engn, Daegu 42988, South Korea

[6] DGIST, DGIST ETH Microrobot Res Ctr, Daegu 42988, South Korea

[7] DGIST, Div Biotechnol, Daegu 42988, South Korea

来源：

APPLIED SURFACE SCIENCE | 2021年 / 562卷

关键词：

Poly(vinylidene fluoride) (PVDF); Poly(vinylidene fluoride-co-chlorotrifluoroethylene) (PVDF-CTFE); Graft copolymer; Antimicrobial activity; Polymer blends; Biocompatibility; POLYVINYLIDENE FLUORIDE; BACTERIALLY ANTIADHESIVE; RADICAL-POLYMERIZATION; FOULING RESISTANCE; CATIONIC BIOCIDES; PVDF MEMBRANE; IONIC LIQUID; ANTIBACTERIAL; IMMOBILIZATION; FABRICATION;

D O I：

10.1016/j.apsusc.2021.150181

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Poly(vinylidene fluoride) (PVDF) and its copolymers have been extensively utilized owing to their fascinating properties such as thermal stability, chemical resistance, and mechanical robustness. However, their lack of microbial resistance is considered a drawback that limits their adoption as biomedical materials. In this study, to overcome this problem, PVDF-based antimicrobial polymers were prepared by grafting quaternary ammonium or quaternary pyridinium monomers. The polymers could effectively kill gram-positive S. aureus, gram-negative E. coli, and the pathogenic yeast C. albicans (antimicrobial rates > 99.99%). Using the polymer blending method, 1 wt% or 5 wt% of the polymers were added to the pristine PVDF film to provide antimicrobial properties. The blend films exhibited enhanced mechanical properties compared to those of pristine PVDF and notably higher antimicrobial performances (>99% for Blend-Q4VP-5); moreover, they were all biocompatible.

引用

页数：9

共 51 条

[51] Antibiofouling Polyvinylidene Fluoride Membrane Modified by Quaternary Ammonium Compound: Direct Contact-Killing versus Induced Indirect Contact-Killing [J].

Zhang, Xingran ;

Ma, Jinxing ;

Tang, Chuyang Y. ;

Wang, Zhiwei ;

Ng, How Yong ;

Wut, Zhichao .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 50 (10) :5086-5093

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