Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11

被引:5
作者
Armbrust, Robert [1 ,2 ,3 ,4 ,5 ,6 ]
Chen, Frank [1 ,2 ,3 ,4 ,5 ,6 ]
Richter, Rolf [1 ,2 ,3 ,4 ,5 ,6 ]
Muallem, Mustafa Zela [1 ,2 ,3 ,4 ,5 ,6 ]
Mustea, Alexander [7 ]
Holthaus, Bernd [8 ]
Sehouli, Jalid [1 ,2 ,3 ,4 ,5 ,6 ]
机构
[1] Ctr Oncol Surg, Dept Gynecol, Augustenburger Pl 1, D-13353 Berlin, Germany
[2] Free Univ Berlin, Augustenburger Pl 1, D-13353 Berlin, Germany
[3] Humboldt Univ, Augustenburger Pl 1, D-13353 Berlin, Germany
[4] Berlin Inst Hlth, Augustenburger Pl 1, D-13353 Berlin, Germany
[5] Charite, Virchow Campus Clin, Augustenburger Pl 1, D-13353 Berlin, Germany
[6] Free Univ Berlin, Berlin Inst Hlth, Berlin, Germany
[7] Univ Bonn, Dept Gynecol, Bonn, Germany
[8] Kardinal Von Galen Kliniken Damme, Working Grp Gynecol Endoscopy, Dept Gynecol, Damme, Germany
关键词
INVASIVE RADICAL HYSTERECTOMY; CLASSIFICATION; OUTCOMES; LACC;
D O I
10.1038/s41598-021-89071-0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Minimally invasive surgery (MIS) has become the standard approach in early stage cervical cancer (ECC). However, the recently published "LACC" trial and even others could show inferior PFS and OS of MIS compared to open radical hysterectomy. The results led to a widespread debate about the best surgical approach in ECC. The present survey aimed to get first insights after publication. NOGGO and AGE conducted a nationwide digital survey among 186 Gynecological Cancer Centers. Descriptive statistics and t-tests were performed using SPSS. A majority of the centers were of high expertise and/or experience in treatment of ECC and were highly aware of the LACC trial results. Trial quality and scientific value were rated as very good/good. However, still 40% would not change the standard of care to open surgery. Centers with higher volume and participating in clinical trials were more likely to change. This survey represents insights after the surprising results of recently published trials towards the surgical approach of ECC. There still seems to be a high need of future trials and possible explanations for the unexpected worse outcomes in the MIS group.
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页数:5
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