The effect of asymmetry on micromixing in curvilinear microchannels

被引:19
作者
Akgonul, Sarp [1 ]
Ozbey, Arzu [1 ]
Karimzadehkhouei, Mehrdad [1 ]
Gozuacik, Devrim [2 ,3 ]
Kosar, Ali [1 ,3 ]
机构
[1] Sabanci Univ, Fac Engn & Nat Sci, Mechatron Engn Program, TR-34956 Istanbul, Turkey
[2] Sabanci Univ, Fac Engn & Nat Sci, Biol Sci & Bioengn Program, TR-34956 Istanbul, Turkey
[3] Sabanci Univ, Ctr Excellence Funct Surfaces & Interfaces EFSUN, TR-34956 Istanbul, Turkey
关键词
Passive mixing; Chaotic advection; Dean vortices; Curvilinear PDMS microchannel; Asymmetrical channel; MICROFLUIDIC SYSTEMS; CHEMICAL-REACTIONS; MIXER; CHANNELS; DESIGN;
D O I
10.1007/s10404-017-1952-1
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The necessity of microscale mixing processes has been tremendously increasing in most of the micro-size chemical and biochemical devices during recent years, particularly in the design of lab-on-a-chip and micrototal analysis systems. Different approaches were implemented in the available micromixers in the literature for improving the mixing performance. Due to the absence of any external source, mixing by utilizing passive mixing techniques is more economical. In curvilinear microchannels, which offer effective passive mixing, chaotic advection results in continuous radial perforation of inter-diffusion layer between the fluid streams due to the transverse secondary flows. In this study, the effects of Dean vortices and secondary flows were investigated in asymmetrical polydimethylsiloxane curvilinear rectangular microchannels, which were fabricated by one-step lithography process and had repeated S-shape patterns with a curvature of 280 degrees along the channel. Moreover, the effect of asymmetry was assessed by comparing the mixing results with symmetrical microchannels. Mixing performance was analyzed by using NaOH and phenolphthalein solutions as mixing fluids, which entered from the channel inlets. According to the results, the significant effects of stretching and contracting motion of Dean vortices revealed themselves above a certain Dean number value, thereby making the asymmetrical microchannel outperform the symmetrical channel in the mixing performance. Below this threshold, the symmetrical microchannel was observed to be superior to the asymmetrical microchannel.
引用
收藏
页数:15
相关论文
共 41 条
[1]   Passive split and recombination micromixer with convergent-divergent walls [J].
Afzal, Arshad ;
Kim, Kwang-Yong .
CHEMICAL ENGINEERING JOURNAL, 2012, 203 :182-192
[2]   Mixing performance of a planar micromixer with circular obstructions in a curved microchannel [J].
Alam, Afroz ;
Afzal, Arshad ;
Kim, Kwang-Yong .
CHEMICAL ENGINEERING RESEARCH & DESIGN, 2014, 92 (03) :423-434
[3]   Design of micromixers using CFD modelling [J].
Aubin, J ;
Fletcher, DF ;
Xuereb, C .
CHEMICAL ENGINEERING SCIENCE, 2005, 60 (8-9) :2503-2516
[4]   Physics and applications of microfluidics in biology [J].
Beebe, DJ ;
Mensing, GA ;
Walker, GM .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2002, 4 :261-286
[5]   A highly efficient 3D micromixer using soft PDMS bonding [J].
Cha, Junghun ;
Kim, Jinseok ;
Ryu, Suk-Kyu ;
Park, Jungyul ;
Jeong, Yongwon ;
Park, Sewan ;
Park, Sukho ;
Kim, Hyeon Cheol ;
Chun, Kukjin .
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2006, 16 (09) :1778-1782
[6]   Optimal Designs of Staggered Dean Vortex Micromixers [J].
Chen, Jyh Jian ;
Chen, Chun Huei ;
Shie, Shian Ruei .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2011, 12 (06) :3500-3524
[7]   Analysis of chaos and FRET reaction in split-and-recombine microreactors [J].
Chen, Yu-Tzu ;
Fang, Wei-Feng ;
Liu, Yen-Cheng ;
Yang, Jing-Tang .
MICROFLUIDICS AND NANOFLUIDICS, 2011, 11 (03) :339-352
[8]   Mixing Evaluation of a Passive Scaled-Up Serpentine Micromixer With Slanted Grooves [J].
Cook, Kristina J. ;
Fan, YanFeng ;
Hassan, Ibrahim .
JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, 2013, 135 (08)
[9]   Control and detection of chemical reactions in microfluidic systems [J].
deMello, Andrew J. .
NATURE, 2006, 442 (7101) :394-402
[10]   Rapid microfluidic mixer utilizing sharp corner structures [J].
Fan, Liang-Liang ;
Zhu, Xiao-Liang ;
Zhao, Hong ;
Zhe, Jiang ;
Zhao, Liang .
MICROFLUIDICS AND NANOFLUIDICS, 2017, 21 (03)