Translational Research: The Model Matters

被引:1
作者
Deutschman, Clifford S. [1 ,2 ]
机构
[1] Elmezzi Grad Sch Mol Med, Hofstra Northwell Sch Med, Dept Pediat, Manhasset, NY 11030 USA
[2] Feinstein Inst Med Res, Manhasset, NY 11030 USA
关键词
animal models; antibiotics resuscitation; sepsis; septic shock; INTERNATIONAL CONSENSUS DEFINITIONS; SEPTIC SHOCK; CLINICAL-CRITERIA; SEPSIS;
D O I
10.1097/CCM.0000000000003033
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:835 / 837
页数:3
相关论文
共 13 条
  • [1] The New Sepsis Definitions: Implications for the Basic and Translational Research Communities
    Coopersmith, Craig M.
    Deutschman, Clifford S.
    [J]. SHOCK, 2017, 47 (03): : 264 - 268
  • [2] Sepsis: Current Dogma and New Perspectives
    Deutschman, Clifford S.
    Tracey, Kevin J.
    [J]. IMMUNITY, 2014, 40 (04) : 464 - 476
  • [3] Orexinergic Activity Modulates Altered Vital Signs and Pituitary Hormone Secretion in Experimental Sepsis
    Deutschman, Clifford S.
    Raj, Nichelle R.
    McGuire, Erin O.
    Kelz, Max B.
    [J]. CRITICAL CARE MEDICINE, 2013, 41 (11) : E368 - E375
  • [4] Sepsis and septic shock
    Hotchkiss, Richard S.
    Moldawer, Lyle L.
    Opal, Steven M.
    Reinhart, Konrad
    Turnbull, Isaiah R.
    Vincent, Jean-Louis
    [J]. NATURE REVIEWS DISEASE PRIMERS, 2016, 2
  • [5] Mortality Related to Severe Sepsis and Septic Shock Among Critically III Patients in Australia and New Zealand, 2000-2012
    Kaukonen, Kirsi-Maija
    Bailey, Michael
    Suzuki, Satoshi
    Pilcher, David
    Bellomo, Rinaldo
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 311 (13): : 1308 - 1316
  • [6] Prompt Administration of Antibiotics and Fluids in the Treatment of Sepsis: A Murine Trial
    Lewis, Anthony J.
    Griepentrog, John E.
    Zhang, Xianghong
    Angus, Derek C.
    Seymour, Christopher W.
    Rosengart, Matthew R.
    [J]. CRITICAL CARE MEDICINE, 2018, 46 (05) : E426 - E434
  • [7] Use of Biotelemetry to Define Physiology-Based Deterioration Thresholds in a Murine Cecal Ligation and Puncture Model of Sepsis
    Lewis, Anthony J.
    Yuan, Du
    Zhang, Xianghong
    Angus, Derek C.
    Rosengart, Matthew R.
    Seymour, Christopher W.
    [J]. CRITICAL CARE MEDICINE, 2016, 44 (06) : E420 - E431
  • [8] SEPSIS-3 ON THE BLOCK: WHAT DOES IT MEAN FOR PRECLINICAL SEPSIS MODELING?
    Osuchowski, Marcin F.
    Thiemermann, Christoph
    Remick, Daniel G.
    [J]. SHOCK, 2017, 47 (05): : 658 - 660
  • [9] Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
    Rhodes, Andrew
    Evans, Laura E.
    Alhazzani, Waleed
    Levy, Mitchell M.
    Antonelli, Massimo
    Ferrer, Ricard
    Kumar, Anand
    Sevransky, Jonathan E.
    Sprung, Charles L.
    Nunnally, Mark E.
    Rochwerg, Bram
    Rubenfeld, Gordon D.
    Angus, Derek C.
    Annane, Djillali
    Beale, Richard J.
    Bellinghan, Geoffrey J.
    Bernard, Gordon R.
    Chiche, Jean-Daniel
    Coopersmith, Craig
    De Backer, Daniel P.
    French, Craig J.
    Fujishima, Seitaro
    Gerlach, Herwig
    Hidalgo, Jorge Luis
    Hollenberg, Steven M.
    Jones, Alan E.
    Karnad, Dilip R.
    Kleinpell, Ruth M.
    Koh, Younsuck
    Lisboa, Thiago Costa
    Machado, Flavia R.
    Marini, John J.
    Marshall, John C.
    Mazuski, John E.
    McIntyre, Lauralyn A.
    McLean, Anthony S.
    Mehta, Sangeeta
    Moreno, Rui P.
    Myburgh, John
    Navalesi, Paolo
    Nishida, Osamu
    Osborn, Tiffany M.
    Perner, Anders
    Plunkett, Colleen M.
    Ranieri, Marco
    Schorr, Christa A.
    Seckel, Maureen A.
    Seymour, Christopher W.
    Shieh, Lisa
    Shukri, Khalid A.
    [J]. CRITICAL CARE MEDICINE, 2017, 45 (03) : 486 - 552
  • [10] Time to Treatment and Mortality during Mandated Emergency Care for Sepsis
    Seymour, Christopher W.
    Gesten, Foster
    Prescott, Hallie C.
    Friedrich, Marcus E.
    Iwashyna, Theodore J.
    Phillips, Gary S.
    Lemeshow, Stanley
    Osborn, Tiffany
    Terry, Kathleen M.
    Levy, Mitchell M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (23) : 2235 - 2244