Membranous nephropathy with Neuromyelitis optica spectrum disorder

被引：8

作者：

Li, Xiangling ^{[1
]}

Wang, YanQiang ^{[2
]}

机构：

[1] Wei Fang Med Univ, Affiliated Hosp, Dept Internal Med, Dept Nephrol, Weifang, Peoples R China

[2] Wei Fang Med Univ, Affiliated Hosp, Dept Neurol, 2428 Yuhe Rd, Weifang 261031, Shandong, Peoples R China

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2017年 / 15卷

关键词：

Membranous nephropathy; Neuromyelitis optica spectrum disorders; Proteinuria; Intractable hiccup and vomiting; CLINICAL-CHARACTERISTICS;

D O I：

10.1016/j.msard.2017.05.007

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Membranous nephropathy (MN) accompanying Neuromyelitis optica spectrum disorders (NMOSD) has rarely been described previously. We recently presented a 45-year-old Chinese male presenting with recurrent lower extremity pitting edema, or eyelid edema, proteinuria and hyperlipidemia. especially intractable hiccup and vomiting, painful tonic spasm (PTS) as the revealing symptom of a demyelinating disorder of central nervous system. The kindey biopsy specimen showed MN stage 2. Serological testing revealed antibodies AQP4, MRI head and spine revealed medulla oblongata and C1-C2 cervical vertebra lesions. Treatment with methylprednisolone, cyclophosphamide, azathioprine resulted in consistent clinical improvement.

引用

页码：49 / 51

页数：3

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