Design of chiral auxiliaries for the allene ether Nazarov cyclization

被引：41
作者：
Banaag, April R.
Tius, Marcus A.
机构：
[1] Univ Hawaii, Dept Chem, Honolulu, HI 96822 USA
[2] Canc Res Ctr Hawaii, Honolulu, HI 96813 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 17期
关键词：
D O I：
10.1021/ja069342g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A 1,3- or a 1,4-cis axial tert-butyldimethylsilyloxy substituent on the pyranose derived chiral auxiliary for the allene ether Nazarov cyclization leads to products in high optical purity. alpha-Pyranose and beta-pyranose derived auxiliaries lead to enantiomeric products.
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页码：5328 / +
页数：3
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