Regulation of membrane fusion in synaptic excitation-secretion coupling: Speed and accuracy matter

被引：140

作者：

Wojcik, Sonja M. ^{[1
]}

Brose, Nils ^{[1
]}

机构：

[1] Max Planck Inst Expt Med, Abt Mol Neurobiol, D-37075 Gottingen, Germany

来源：

NEURON | 2007年 / 55卷 / 01期

关键词：

D O I：

10.1016/j.neuron.2007.06.013

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Unlike most other secretory processes, neurotransmitter release at chemical synapses is extremely fast, tightly regulated, spatially restricted, and dynamically adjustable at the same time. In this review, we focus on recent discoveries of molecular and cell biological processes that determine how fusion competence of vesicles is achieved and controlled in order to suit the specific requirements of synaptic transmitter release with respect to speed and spatial selectivity.

引用

页码：11 / 24

页数：14

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