Ru/C catalyzed cyclization of linear α,ω-diamines to cyclic amines in water

被引：21

作者：

Gadda, Thomas M. ^{[1
]}

Yu, Xiao-Yan ^{[1
]}

Miyazawa, Akira ^{[1
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, NRI, Higashi Ku, Tsukuba, Ibaraki 3058565, Japan

来源：

TETRAHEDRON | 2010年 / 66卷 / 06期

关键词：

Cyclic amine; Ru/C; Synthesis; Water; Cyclization; Intramolecular; Ring-closure; Deuteration; SECONDARY-AMINES; CONVENIENT SYNTHESIS; TERTIARY-AMINES; PIPERIDINES; REDUCTION; TRANSFORMATION; RUCL2(PH3P)3; AZIRIDINES; CONVERSION; ALKENES;

D O I：

10.1016/j.tet.2009.12.025

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile and convenient way to prepare cyclic amines in water was achieved by the catalyst system composed of Ru/C and Al powder The alpha,omega-diaminoalkanes, 1.4-diaminobutane, 1,5-diaminopentane. and 1.6-diamino-heptane were converted to corresponding cyclic amines in good yields The Use Of D2O provided a novel route to obtain deuterated cyclic amines in good yields (C) 2009 Elsevier Ltd All rights reserved

引用

页码：1249 / 1253

页数：5

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