Near infra-red reflectance spectroscopic determination of metformin in tablets

被引：47

作者：

Habib, IHI ^{[1
]}

Kamel, MS ^{[1
]}

机构：

[1] Natl Res Ctr, Microanalyt Chem Lab, Cairo, Egypt

来源：

TALANTA | 2003年 / 60卷 / 01期

关键词：

NIR; metformin; tablet;

D O I：

10.1016/S0039-9140(03)00123-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A rapid and simple near infra red reflectance spectroscopic method was described for determination of anti-diabetic tablets. Partial least squares method was applied to the Savitsky-Golay smoothed first derivative spectral data revealed over wavelength range 1000-2500 mn from 11 different pulverized tablet batches in 2-mm quartz cell. The results were agreed well with those obtained by the official British Pharmacopoiea 1998 UV assay of metformin. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：185 / 190

页数：6

共 42 条

[1]

Abou-Dan M, 2001, ASIAN J CHEM, V13, P1

[2] AN INTRODUCTION TO MULTIVARIATE CALIBRATION AND ANALYSIS [J].