Polymerase chain reaction-based detection of lymphatic filariasis

被引：18
作者：
Fischer, P
Boakye, D
Hamburger, J
机构：
[1] Bernhard Nocht Inst Trop Med, D-20359 Hamburg, Germany
[2] Univ Ghana, Noguchi Mem Inst Med Res, Legon, Accra, Ghana
[3] Hebrew Univ Jerusalem, Kuvin Ctr Study Infect & Trop Dis, Jerusalem, Israel
来源：
MEDICAL MICROBIOLOGY AND IMMUNOLOGY | 2003年 / 192卷 / 01期
关键词：
filariasis; diagnosis; blood; sputum; mosquitoes;
D O I：
10.1007/s00430-002-0152-z
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
PCR-based diagnostic assays are promising tools for the monitoring and evaluation of the Global Programme for Elimination of Lymphatic Filariasis. Sensitive and specific assays have been described for the detection of Wuchereria bancrofti, Brugia malayi, or Brugia timori infection in blood, sputum, and vectors. These techniques can be most cost-effective when employed for pool screening, which is important in the later stages of control programs when infection rates of humans and vectors are low, and large numbers of samples must be examined.
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页码：3 / 7
页数：5
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