From the analysis of protein complexes to proteome-wide linkage maps

被引：24
作者：
Legrain, P
Jestin, JL
Schächter, V
机构：
[1] Hybrigenics, F-75012 Paris, France
[2] Inst Pasteur, Unite Chim Organ, F-75724 Paris 15, France
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2000年 / 11卷 / 04期
关键词：
D O I：
10.1016/S0958-1669(00)00117-8
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent advances in genomics have led to the accumulation of an unprecedented amount of data about genes. Proteins, not genes, however sustain function. The traditional approach to protein function analysis has been the design of smart genetic assays and powerful purification protocols to address very specific questions concerning cellular mechanisms. Lately, a number of proteome-wide functional strategies have emerged, giving rise to a new field in biology, proteomics, that addresses the biology of a cell as a whole.
引用
收藏
页码：402 / 407
页数：6
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