The Platinum Chromium Element Stent Platform: from Alloy, to Design, to Clinical Practice

被引:88
作者
Menown, Ian B. A. [1 ]
Noad, Rebecca [1 ]
Garcia, Eulogio J. [2 ]
Meredith, Ian [3 ,4 ]
机构
[1] Craigavon Cardiac Ctr, Craigavon BT63 5QQ, North Ireland
[2] Hosp Clin San Carlos, Madrid, Spain
[3] Monash Med Ctr, Clayton, Vic 3168, Australia
[4] Monash Univ, Clayton, Vic, Australia
关键词
cobalt chromium stent; coronary stent; platinum chromium stent; radial strength; radiopacity; stainless steel stent; strut thickness; CORONARY-ARTERY-DISEASE; TAXUS LIBERTE STENT; ISAR-STEREO TRIAL; STRUT THICKNESS; RESTENOSIS; PLACEMENT; LESIONS; IMPACT; RISK;
D O I
10.1007/s12325-010-0022-9
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Despite advances in polymer and drug technology, the underlying stent platform remains a key determinant of clinical outcome. A clear understanding of stent design and the differences between various stent platforms are of increasing importance for the interventional cardiologist. Reduction in stent strut thickness has been associated with improved stent deliverability, improved procedural outcome, and lower rates of subsequent restenosis. Newer-generation 316L-SS stent designs have enabled reduced strut thickness while retaining radial strength and minimizing recoil, but with significant loss of radiopacity, leading to reduced visibility. Cobalt chromium alloys have enabled a reduction in stent strut thickness to around 80-90 mm while retaining modest radiopacity, but due to higher elastic properties, have been associated with greater stent recoil. Development of a novel 33% platinum chromium alloy with high radial strength and high radiopacity has enabled design of a new, thin-strut, flexible, easily visualized, and highly trackable stent platform, the use of which is further illustrated in several clinical case descriptions.
引用
收藏
页码:129 / 141
页数:13
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