Ideal Cardiovascular Health Metrics Are Associated with Disability Independently of Vascular Conditions

被引:11
作者
Devulapalli, Saravana [1 ]
Shoirah, Hazem [1 ]
Dhamoon, Mandip S. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Dept Neurol, New York, NY 10029 USA
关键词
WHITE-MATTER; DISEASE; IMPACT;
D O I
10.1371/journal.pone.0150282
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Vascular risk factors may be associated with disability independently of vascular events. We examined whether the American Heart Association's 7 ideal cardiovascular health (CVH) metrics were independently associated with disability in a nationally representative cohort. Methods Adults age >= 20 years from the National Health and Nutrition Examination Survey 20052012 were included. Ideal CVH was calculated as a composite of 7 measures, each scored 0-2. Primary predictors were number of ideal CVH metrics and score of CVH metrics. The outcome was a dichotomous score from 20 activities of daily living (ADL) and instrumental ADLs. Unadjusted and adjusted weighted logistic models estimated associations between ideal CVH and disability. The data were analyzed in 2015. Results Among 22692 participants, mean age was 46.9 years. Cardiac disease and stroke were present in 6.6% and 2.8%; 90.3% had poor physical activity and 89.9% poor diet. Among 3975 individuals with full CVH data, in fully adjusted models, OR for disability was 0.90 (95% CI 0.83-0.98) per point increase in ideal CVH score, and 0.84 (0.73-0.97) per additional number of ideal CVH metrics. Conclusions CVH metrics were strongly and significantly associated with reduced odds of disability independently of vascular and non-vascular conditions. Poorer CVH may cause subclinical vascular disease resulting in disability.
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页数:10
相关论文
共 17 条
[1]   Empirical Support for Cardiovascular Health The Case Gets Even Stronger [J].
Appel, Lawrence J. .
CIRCULATION, 2012, 125 (08) :973-974
[2]   Functional Consequences of Subcortical White Matter Lesions and MRI-Defined Brain Infarct in an Elderly General Population [J].
Baune, Bernhard T. ;
Schmidt, Wolf P. ;
Roesler, Andreas ;
Berger, Klaus .
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, 2009, 22 (04) :266-273
[3]  
BRAULT M W., 2008, American with disabilities: 2005
[4]  
Centers for Disease Control and Prevention, 2015, NHANES SPEC WEIGHT P
[5]  
Centers for Disease Control and Prevention, 2015, NHANES SURV METH
[6]  
Crichton GE, 2014, PLOS ONE, V9, DOI [10.1371/journal.pone.0099829, 10.1371/journal.pone.0089317]
[7]  
Dhamoon MS, 2015, J AM HEART ASSOC, P4
[8]   Ideal Cardiovascular Health and Mortality From All Causes and Diseases of the Circulatory System Among Adults in the United States [J].
Ford, Earl S. ;
Greenlund, Kurt J. ;
Hong, Yuling .
CIRCULATION, 2012, 125 (08) :987-995
[9]  
Hollar Jr DW, 2015, DISABILITY HLTH J, V8, P51, DOI [10. 1016/ j. dhjo. 2014.07.007, DOI 10.1016/J.DHJ0.2014.07.007]
[10]   Cognitive function, habitual gait speed, and late-life disability in the National Health and Nutrition Examination Survey (NHANES) 1999-2002 [J].
Kuo, Hsu-Ko ;
Leveille, Suzanne G. ;
Yu, Yau-Hua ;
Milberg, William P. .
GERONTOLOGY, 2007, 53 (02) :102-110