Allergic conjunctivitis in contact lens wearers: challenges and management recommendations

Introduction: Giant papillary conjunctivitis (GPC), which is the most severe type of contact lens- induced (CL) papillary conjunctivitis (CLPC), is an inflammatory condition of the upper tarsal conjunctiva. Major symptoms of CLPC include irritation, pain, itching, and redness of the ocular surface. Area covered: This review provides an update on our current understanding of the pathogenesis and treatment of GPC. Expert opinion: GPC is most often associated with the use of non-disposable soft contact lenses (SCL), or soft hydrogel lenses, and infrequent CL replacement. Patients with GPC may require both temporary cessation of CL wear and treatment with medications such as topical mast cell stabilizers, antihistamines, non-steroidal anti-inflammatory agents, or steroids.