A Comprehensive Review on Selenium and Its Effects on Human Health and Distribution in Middle Eastern Countries

被引:101
作者
Kieliszek, Marek [1 ]
Bano, Iqra [2 ]
Zare, Hamed [3 ]
机构
[1] Warsaw Univ Life Sci SGGW, Inst Food Sci, Dept Food Biotechnol & Microbiol, Nowoursynowska 159C, PL-02776 Warsaw, Poland
[2] Shaheed Benazir Bhutto Univ Vet & Anim Sci, Dept Vet Physiol & Biochem, Sakrand 67210, Sindh, Pakistan
[3] Birjand Univ Med Sci, Cellular & Mol Res Ctr, Birjand, Iran
关键词
Selenium; Selenoproteins; Human health; Middle East; GPx; UMBILICAL-CORD BLOOD; SERUM SELENIUM; GLUTATHIONE-PEROXIDASE; DIETARY SELENIUM; CARDIOVASCULAR-DISEASE; SELENOPROTEIN-P; THIOREDOXIN REDUCTASE; ALZHEIMERS-DISEASE; CURRENT KNOWLEDGE; GENE-EXPRESSION;
D O I
10.1007/s12011-021-02716-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Selenium (Se) is an important microelement with numerous positive effects on human health and diseases. It is important to specify that the status and consumption of Se are for a specific community as the levels of Se are extremely unpredictable between different populations and regions. Our existing paper was based on the impacts of Se on human health and disease along with data on the Se levels in Middle Eastern countries. Overall, the findings of this comprehensive review show that the consumption and levels of Se are inadequate in Middle Eastern nations. Such findings, together with the growing awareness of the importance of Se to general health, require further work primarily on creating an acceptable range of blood Se concentration or other measures to determine optimal Se consumption and, consequently, to guarantee adequate Se supplementation in populations at high risk of low Se intake.
引用
收藏
页码:971 / 987
页数:17
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