SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022

被引：60

作者：

Sievers, Claudia ^{[1
,2
,3
]}

Zacher, Benedikt ^{[1
]}

Ullrich, Alexander ^{[1
]}

Huska, Matthew ^{[4
]}

Fuchs, Stephan ^{[4
]}

Buda, Silke ^{[1
]}

Haas, Walter ^{[1
]}

Diercke, Michaela ^{[1
]}

an der Heiden, Matthias ^{[1
]}

Kroeger, Stefan ^{[1
]}

机构：

[1] Robert Koch Inst, Dept Infect Dis Epidemiol, Berlin, Germany

[2] Robert Koch Inst, Postgrad Training Appl Epidemiol PAE, Berlin, Germany

[3] European Ctr Dis Prevent & Control ECDC, European Programme Intervent Epidemiol Training E, Stockholm, Sweden

[4] Robert Koch Inst, Dept Genome Sequencing & Genom Epidemiol, Berlin, Germany

来源：

EUROSURVEILLANCE | 2022年 / 27卷 / 22期

关键词：

D O I：

10.2807/1560-7917.ES.2022.27.22.2200396

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in = 35-year- olds. Hospitalised vaccinated Omicron cases' proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.

引用

页数：7

共 19 条

[11]

Robert Koch Institut (RKI), 2022, B1351 2022 04 05, DOI 10.5281/zenodo.6503290

[12]

Robert Koch Institut (RKI), 2022, WOCH LAG RKI

[13]

Schilling J, 2021, BUNDESGESUNDHEITSBLA, V64, P1093, DOI 10.1007/s00103-021-03394-x

[14]

Statistic South Africa, 2019, STAT REL P0302 MID P

[15] Reduced risk of hospitalisation among reported COVID-19 cases infected with the SARS-CoV-2 Omicron BA.1 variant compared with the Delta variant, Norway, December 2021 to January 2022 [J].

Veneti, Lamprini ;

Boas, Hakon ;

Kristoffersen, Anja Brathen ;

Stalcrantz, Jeanette ;

Bragstad, Karoline ;

Hungnes, Olav ;

Storm, Margrethe Larsdatter ;

Aasand, Nina ;

Ro, Gunnar ;

Starrfelt, Jostein ;

Seppala, Elina ;

Kvale, Reidar ;

Vold, Line ;

Nygard, Karin ;

Buanes, Eirik Alnes ;

Whittaker, Robert .

EUROSURVEILLANCE, 2022, 27 (04)

[16] Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa [J].

Viana, Raquel ;

Moyo, Sikhulile ;

Amoako, Daniel G. ;

Tegally, Houriiyah ;

Scheepers, Cathrine ;

Althaus, Christian L. ;

Anyaneji, Ugochukwu J. ;

Bester, Phillip A. ;

Boni, Maciej F. ;

Chand, Mohammed ;

Choga, Wonderful T. ;

Colquhoun, Rachel ;

Davids, Michaela ;

Deforche, Koen ;

Doolabh, Deelan ;

du Plessis, Louis ;

Engelbrecht, Susan ;

Everatt, Josie ;

Giandhari, Jennifer ;

Giovanetti, Marta ;

Hardie, Diana ;

Hill, Verity ;

Hsiao, Nei-Yuan ;

Iranzadeh, Arash ;

Ismail, Arshad ;

Joseph, Charity ;

Joseph, Rageema ;

Koopile, Legodile ;

Kosakovsky Pond, Sergei L. ;

Kraemer, Moritz U. G. ;

Kuate-Lere, Lesego ;

Laguda-Akingba, Oluwakemi ;

Lesetedi-Mafoko, Onalethatha ;

Lessells, Richard J. ;

Lockman ;

Lucaci, Alexander G. ;

Maharaj, Arisha ;

Mahlangu, Boitshoko ;

Maponga, Tongai ;

Mahlakwane, Kamela ;

Makatini, Zinhle ;

Marais, Gert ;

Maruapula, Dorcas ;

Masupu, Kereng ;

Matshaba, Mogomotsi ;

Mayaphi, Simnikiwe ;

Mbhele, Nokuzola ;

Mbulawa, Mpaphi B. ;

Mendes, Adriano ;

Mlisana, Koleka .

NATURE, 2022, 603 (7902) :679-+

[17]

Wolter N, 2022, medRxiv, DOI [10.1101/2022.02.17.22271030, 10.1101/2022.02.17.22271030, DOI 10.1101/2022.02.17.22271030]

[18] Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa: a data linkage study [J].

Wolter, Nicole ;

Jassat, Waasila ;

Walaza, Sibongile ;

Welch, Richard ;

Moultrie, Harry ;

Groome, Michelle ;

Amoako, Daniel Gyamfi ;

Everatt, Josie ;

Bhiman, Jinal N. ;

Scheepers, Cathrine ;

Tebeila, Naume ;

Chiwandire, Nicola ;

du Plessis, Mignon ;

Govender, Nevashan ;

Ismail, Arshad ;

Glass, Allison ;

Mlisana, Koleka ;

Stevens, Wendy ;

Treurnicht, Florette K. ;

Makatini, Zinhle ;

Hsiao, Nei-Yuan ;

Parboosing, Raveen ;

Wadula, Jeannette ;

Hussey, Hannah ;

Davies, Mary-Ann ;

Boulle, Andrew ;

von Gottberg, Anne ;

Cohen, Cheryl .

LANCET, 2022, 399 (10323) :437-446

[19]

Yamasoba D., 2022, Cell, V185, P2103, DOI [10.1016/j.cell.2022.04.035, DOI 10.1016/J.CELL.2022.04.035, 10.1101/2022.02.14.480335]

← 1 2 →